SLC5A3 solute carrier family 5 member 3 [Equus caballus (horse)] - Gene

Summary

Gene symbol: SLC5A3
Gene description: solute carrier family 5 member 3
See related: Ensembl:ENSECAG00000059657
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: all
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Genomic context

Location:: chromosome: 26

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	TB-T2T (GCF_041296265.1)	26	NC_091709.1 (37610367..37645746)
RS_2024_08	previous assembly	EquCab3.0 (GCF_002863925.1)	26	NC_009169.3 (31869233..31904230)

Chromosome 26 - NC_091709.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Thoroughbred Stallion gene expression
BioProject: PRJEB53382
Analysis date: Mon Jan 06 09:53:19 2025

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Fatal Foal Immunodeficiency Syndrome in the Fell and Dales pony was associated with a mutation in the sodium/myo-inositol cotransporter gene (SLC5A3),which causes a P446L substitution in the protein.This substitution alters the function of SLC5A3.
Title: Identification of a mutation associated with fatal Foal Immunodeficiency Syndrome in the Fell and Dales pony.

Submit: New GeneRIF Correction

General gene information

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Markers

UniSTS:259143 (e-PCR)
- UniSTS:259143

Slc5a3 (e-PCR), detects polymorphism
- UniSTS:259143

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables D-glucose:sodium symporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in inositol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in myo-inositol transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: sodium/myo-inositol cotransporter

Names: solute carrier family 5 (sodium/myo-inositol cotransporter), member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.