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h3c14.L H3 clustered histone 14 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100049126, updated on 4-Feb-2026
Official Symbol
h3c14.L
Official Full Name
H3 clustered histone 14 L homeolog
Primary source
Xenbase:XB-GENE-866635
Locus tag
XELAEV_18004100mg
See related
AllianceGenome:Xenbase:XB-GENE-866635
Gene type
protein coding
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
hist2h3c; hist2h3c.L
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleoplasm. Predicted to be part of nucleosome. Orthologous to human H3C14 (H3 clustered histone 14). [provided by Alliance of Genome Resources, Apr 2025]
Annotation information
not in current annotation release
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Related articles in PubMed

  1. Individual Xenopus histone genes are replication-independent in oocytes and replication-dependent in Xenopus or mouse somatic cells. Old RW, et al. Nucleic Acids Res, 1985 Oct 25. PMID 4059058, Free PMC Article
  2. Disordered region of H3K9 methyltransferase Clr4 binds the nucleosome and contributes to its activity. Akoury E, et al. Nucleic Acids Res, 2019 Jul 26. PMID 31165882, Free PMC Article
  3. Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements. Perry M, et al. J Mol Biol, 1985 Oct 5. PMID 3863963
  4. Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. Davey CA, et al. J Mol Biol, 2002 Jun 21. PMID 12079350
  5. Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity. Manni I, et al. Mol Biol Cell, 2008 Dec. PMID 18815279, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within heterochromatin formation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
part_of nucleosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
histone H3.2
Names
histone cluster 2, H3c L homeolog

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Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001097959.1: Suppressed sequence

    Description
    NM_001097959.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P84233.2 GenPept UniProtKB/Swiss-Prot:P84233

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