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Zfp850 zinc finger protein 850 [ Mus musculus (house mouse) ]

Gene ID: 100043772, updated on 8-Feb-2024

Summary

Official Symbol
Zfp850provided by MGI
Official Full Name
zinc finger protein 850provided by MGI
Primary source
MGI:MGI:3036281
See related
Ensembl:ENSMUSG00000096916 AllianceGenome:MGI:3036281
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm4636; C130069I09Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF780A (zinc finger protein 780A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

Location:
7 A3; 7 15.97 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (27683896..27713634, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27984471..28014210, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 780B Neighboring gene STARR-positive B cell enhancer ABC_E2231 Neighboring gene vomeronasal 1 receptor, pseudogene 87 Neighboring gene STARR-positive B cell enhancer ABC_E1084 Neighboring gene STARR-seq mESC enhancer starr_18400 Neighboring gene proteasome (prosome, macropain) 26S subunit, ATPase, 4 Neighboring gene Fc fragment of IgG binding protein Neighboring gene tectorin alpha pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Clone Names

  • MGC35631

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001254951.1NP_001241880.1  zinc finger protein 850

    See identical proteins and their annotated locations for NP_001241880.1

    Status: VALIDATED

    Source sequence(s)
    AC139063, AC158220, BU925220, CF735501
    Consensus CDS
    CCDS57531.1
    UniProtKB/TrEMBL
    A0A087WSI7, J3QPC5
    Related
    ENSMUSP00000141063.3, ENSMUST00000180502.8
    Conserved Domains (4) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:279671
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:202222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:256278
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    27683896..27713634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250406.4XP_011248708.1  zinc finger protein 850 isoform X1

    See identical proteins and their annotated locations for XP_011248708.1

    UniProtKB/TrEMBL
    A0A087WSI7, J3QPC5
    Related
    ENSMUSP00000137192.2, ENSMUST00000180024.2
    Conserved Domains (4) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:279671
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:202222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:256278
    zf-C2H2; Zinc finger, C2H2 type
  2. XM_011250405.4XP_011248707.1  zinc finger protein 850 isoform X1

    See identical proteins and their annotated locations for XP_011248707.1

    UniProtKB/TrEMBL
    A0A087WSI7, J3QPC5
    Conserved Domains (4) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:279671
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:202222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:256278
    zf-C2H2; Zinc finger, C2H2 type
  3. XM_011250404.4XP_011248706.1  zinc finger protein 850 isoform X1

    See identical proteins and their annotated locations for XP_011248706.1

    UniProtKB/TrEMBL
    A0A087WSI7, J3QPC5
    Conserved Domains (4) summary
    smart00349
    Location:1475
    KRAB; krueppel associated box
    COG5048
    Location:279671
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:202222
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:256278
    zf-C2H2; Zinc finger, C2H2 type
  4. XM_036152497.1XP_036008390.1  zinc finger protein 850 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:244636
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:167187
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:221243
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1840
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  5. XM_030241930.2XP_030097790.1  zinc finger protein 850 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:244636
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:167187
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:221243
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1840
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  6. XM_036152496.1XP_036008389.1  zinc finger protein 850 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:244636
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:167187
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:221243
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1840
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001100456.1: Suppressed sequence

    Description
    NM_001100456.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.