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Mir22hg Mir22 host gene (non-protein coding) [ Mus musculus (house mouse) ]

Gene ID: 100042498, updated on 3-Apr-2024

Summary

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Official Symbol
Mir22hgprovided by MGI
Official Full Name
Mir22 host gene (non-protein coding)provided by MGI
Primary source
MGI:MGI:1914348
See related
Ensembl:ENSMUSG00000085148 AllianceGenome:MGI:1914348
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mir-22; 2210403K04Rik
Summary
Acts upstream of or within response to wounding. Orthologous to human MIR22HG (MIR22 host gene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 25.8), placenta adult (RPKM 10.6) and 28 other tissues See more
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Genomic context

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See Mir22hg in Genome Data Viewer
Location:
11 B5; 11 45.91 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (75352365..75357516)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (75461539..75466690)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene serine (or cysteine) peptidase inhibitor, clade F, member 2 Neighboring gene predicted gene, 35391 Neighboring gene WD repeat domain 81 Neighboring gene STARR-positive B cell enhancer ABC_E3973 Neighboring gene STARR-positive B cell enhancer ABC_E10687 Neighboring gene STARR-seq mESC enhancer starr_29995 Neighboring gene microRNA 22 Neighboring gene TLC domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E591 Neighboring gene pre-mRNA processing factor 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway. Li Y, et al. Mol Med, 2023 Apr 20. PMID 37081396, Free PMC Article
  2. Long non-coding RNA MIR22HG promotes osteogenic differentiation of bone marrow mesenchymal stem cells via PTEN/ AKT pathway. Jin C, et al. Cell Death Dis, 2020 Jul 30. PMID 32732881, Free PMC Article
  3. Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice. Schweisgut J, et al. EMBO J, 2017 May 2. PMID 28314781, Free PMC Article
  4. Identification of candidate long non-coding RNAs in response to myocardial infarction. Zangrando J, et al. BMC Genomics, 2014 Jun 10. PMID 24917243, Free PMC Article
  5. miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, et al. Nucleic Acids Res, 2011 Jan. PMID 21037258, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway.
    Title: Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway.
  2. Long non-coding RNA MIR22HG promotes osteogenic differentiation of bone marrow mesenchymal stem cells via PTEN/ AKT pathway.
    Title: Long non-coding RNA MIR22HG promotes osteogenic differentiation of bone marrow mesenchymal stem cells via PTEN/ AKT pathway.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (2) 

General gene information

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Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within response to wounding IEP
Inferred from Expression Pattern
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_030711.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL591496
    Related
    ENSMUST00000149940.2

  2. NR_190554.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL591496

  3. NR_190555.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL591496

  4. NR_190556.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL591496

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    75352365..75357516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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