mcl1 MCL1, BCL2 family apoptosis regulator [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: mcl1provided by Xenbase
Official Full Name: MCL1, BCL2 family apoptosis regulatorprovided by Xenbase
Primary source: Xenbase:XB-GENE-487620
See related: Ensembl:ENSXETG00000008910
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: eat; mcl-1; mcl1l; mcl1s; bcl2l3
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (127210198..127215475)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (106581118..106586397)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein homodimerization activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in extrinsic apoptotic signaling pathway in absence of ligand	IBA Inferred from Biological aspect of Ancestor more info
involved_in intrinsic apoptotic signaling pathway in response to DNA damage	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of apoptotic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in release of cytochrome c from mitochondria	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial outer membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info

Preferred Names: induced myeloid leukemia cell differentiation protein Mcl-1

Names: myeloid cell leukemia 1; myeloid cell leukemia sequence 1 (BCL2-related)

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The following sections contain reference sequences that belong to a specific genome build. Explain