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C6 complement C6 [ Sus scrofa (pig) ]

Gene ID: 100037952, updated on 1-Mar-2025
Official Symbol
C6provided by VGNC
Official Full Name
complement C6provided by VGNC
Primary source
VGNC:VGNC:86050
See related
Ensembl:ENSSSCG00000016861 RGD:14154001
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in liver (RPKM 173.6) and mixtures (RPKM 63.3) See more
Orthologs
human mouse all
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Location:
chromosome: 16
Exon count:
18
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 16 NC_010458.4 (26023646..26089518, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 16 NC_010458.3 (27211345..27261841, complement)

Chromosome 16 - NC_010458.4Genomic Context describing neighboring genes Neighboring gene maestro heat like repeat family member 2B Neighboring gene uncharacterized LOC110257294 Neighboring gene phosphatidylinositol specific phospholipase C X domain containing 3 Neighboring gene NEDD8-conjugating enzyme UBE2F pseudogene

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Related articles in PubMed

  1. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of membrane attack complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
complement component C6
Names
complement component 6

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097449.1 → NP_001090918.1  complement component C6 precursor

    See identical proteins and their annotated locations for NP_001090918.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ333199
    UniProtKB/TrEMBL
    A0A8D1GPQ4, A0SEH0
    Related
    ENSSSCP00000070538.1, ENSSSCT00000085968.2
    Conserved Domains (6) summary
    cd00033
    Location:704 → 762
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00057
    Location:769 → 839
    FIMAC; factor I membrane attack complex
    smart00209
    Location:568 → 612
    TSP1; Thrombospondin type 1 repeats
    cd00112
    Location:142 → 173
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00084
    Location:644 → 699
    Sushi; Sushi repeat (SCR repeat)
    pfam01823
    Location:294 → 514
    MACPF; MAC/Perforin domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010458.4 Reference Sscrofa11.1 Primary Assembly

    Range
    26023646..26089518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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