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Mfap1b microfibrillar-associated protein 1B [ Mus musculus (house mouse) ]

Gene ID: 100034361, updated on 8-Feb-2024

Summary

Official Symbol
Mfap1bprovided by MGI
Official Full Name
microfibrillar-associated protein 1Bprovided by MGI
Primary source
MGI:MGI:3694697
See related
Ensembl:ENSMUSG00000048222 AllianceGenome:MGI:3694697
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mfap1a
Summary
Predicted to be an extracellular matrix structural constituent. Predicted to be involved in mRNA splicing, via spliceosome. Located in collagen-containing extracellular matrix. Is expressed in genitourinary system. Orthologous to human MFAP1 (microfibril associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 37.3), bladder adult (RPKM 21.2) and 22 other tissues See more
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Genomic context

Location:
2 E5; 2 60.4 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (121292147..121304504, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (121461666..121474023, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene small EDRK-rich factor 2 Neighboring gene serine incorporator 4 Neighboring gene huntingtin interacting protein K Neighboring gene WD repeat domain 76 pseudogene Neighboring gene mitochondrial ribosomal protein L51 pseudogene Neighboring gene microfibrillar-associated protein 1A Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:121332344-121332527

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables extracellular matrix structural constituent RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in collagen-containing extracellular matrix HDA PubMed 
located_in microfibril ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
microfibrillar-associated protein 1B
Names
Microfibrillar-associated protein 1A
Spliceosome B complex protein MFAP1A
microfibrillar-associated protein 1
spliceosome B complex protein MFAP1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081975.3NP_001075444.1  microfibrillar-associated protein 1B

    See identical proteins and their annotated locations for NP_001075444.1

    Status: PROVISIONAL

    Source sequence(s)
    AK018514
    Consensus CDS
    CCDS38217.1
    UniProtKB/Swiss-Prot
    C0HKD8, C0HKD9, Q3TU29, Q8CCL1, Q9CQU1, Q9CSJ5
    Related
    ENSMUSP00000049548.4, ENSMUST00000056732.4
    Conserved Domains (1) summary
    pfam06991
    Location:190399
    MFAP1; Microfibril-associated/Pre-mRNA processing

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    121292147..121304504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)