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RYR1 ryanodine receptor 1 [ Equus caballus (horse) ]

Gene ID: 100034090, updated on 8-Aug-2025
Official Symbol
RYR1provided by VGNC
Official Full Name
ryanodine receptor 1provided by VGNC
Primary source
VGNC:VGNC:51076
See related
Ensembl:ENSECAG00000015344
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
all
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See RYR1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
106
Annotation release Status Assembly Chr Location
RS_2024_12 current TB-T2T (GCF_041296265.1) 10 NC_091693.1 (9528730..9635115)
RS_2024_08 previous assembly EquCab3.0 (GCF_002863925.1) 10 NC_009153.3 (9633620..9739087)

Chromosome 10 - NC_091693.1Genomic Context describing neighboring genes Neighboring gene sprouty related EVH1 domain containing 3 Neighboring gene family with sequence similarity 98 member C Neighboring gene RAS guanyl releasing protein 4 Neighboring gene uncharacterized LOC106782291 Neighboring gene uncharacterized LOC138915909 Neighboring gene uncharacterized LOC138915910 Neighboring gene microRNA mir-9087 Neighboring gene mitogen-activated protein kinase kinase kinase kinase 1 Neighboring gene eukaryotic translation initiation factor 3 subunit K Neighboring gene actinin alpha 4 Neighboring gene uncharacterized LOC138915701

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Thoroughbred Stallion gene expression
  • BioProject: PRJEB53382
  • Analysis date: Mon Jan 06 09:53:19 2025

Related articles in PubMed

  1. Association of a mutation in the ryanodine receptor 1 gene with equine malignant hyperthermia. Aleman M, et al. Muscle Nerve, 2004 Sep. PMID 15318347
  2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ryanodine-sensitive calcium-release channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in striated muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in smooth endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
ryanodine receptor 1
Names
ryanodine receptor 1 (skeletal)

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RefSeqs of Annotated Genomes: GCF_041296265.1-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TB-T2T Primary Assembly

Genomic

  1. NC_091693.1 Reference TB-T2T Primary Assembly

    Range
    9528730..9635115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023649662.2 → XP_023505430.2  ryanodine receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2ID92

  2. XM_070224377.1 → XP_070080478.1  ryanodine receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2GYJ2

  3. XM_023649663.2 → XP_023505431.2  ryanodine receptor 1 isoform X2

    UniProtKB/TrEMBL
    F6VR21

  4. XM_070224378.1 → XP_070080479.1  ryanodine receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2GYJ2
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials