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dre-mir-10b-2 microRNA 10b-2 [ Danio rerio (zebrafish) ]

Gene ID: 100033560, updated on 9-Sep-2025
Official Symbol
dre-mir-10b-2provided by ZNC
Official Full Name
microRNA 10b-2provided by ZNC
Primary source
ZFIN:ZDB-MIRNAG-070112-3
See related
Ensembl:ENSDARG00000082918 miRBase:MI0001887; AllianceGenome:ZFIN:ZDB-MIRNAG-070112-3
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mir10b-2
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See dre-mir-10b-2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 23 NC_133198.1 (39234365..39234456)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 23 NC_007134.7 (36130001..36130092)

Chromosome 23 - NC_133198.1Genomic Context describing neighboring genes Neighboring gene si:dkey-81p22.11 Neighboring gene homeobox C3a Neighboring gene homeobox C6a Neighboring gene homeobox C5a Neighboring gene homeobox C4a Neighboring gene homeobox C1a

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Wang X, et al. Cardiovasc Res, 2016 May 1. PMID 26825552
  2. MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Hassel D, et al. Circ Res, 2012 Nov 9. PMID 22955733, Free PMC Article
  3. The zebrafish hoxDb cluster has been reduced to a single microRNA. Woltering JM, et al. Nat Genet, 2006 Jun. PMID 16736008
  4. In silico genome wide mining of conserved and novel miRNAs in the brain and pineal gland of Danio rerio using small RNA sequencing data. Agarwal S, et al. Genom Data, 2016 Mar. PMID 26981358, Free PMC Article
  5. Characterization of small RNAs in early zebrafish PGCs. Zhang X, et al. Acta Biochim Biophys Sin (Shanghai), 2021 Mar 26. PMID 33506864

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Other Names

  • miR-10b-2
  • mirn10b-2

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_034190.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JBMGRA010000023
    Related
    ENSDART00000115942.2

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133198.1 Reference GRCz12tu Primary Assembly

    Range
    39234365..39234456
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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