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dre-mir-430a-18 microRNA 430a-18 [ Danio rerio (zebrafish) ]

Gene ID: 100033493, updated on 9-Sep-2025
Official Symbol
dre-mir-430a-18provided by ZNC
Official Full Name
microRNA 430a-18provided by ZNC
Primary source
ZFIN:ZDB-MIRNAG-090929-250
See related
miRBase:MI0002131; AllianceGenome:ZFIN:ZDB-MIRNAG-090929-250
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mir430a-18
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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See dre-mir-430a-18 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 4 NC_133179.1 (31612592..31612681)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 4 NC_007115.7 (28693199..28693288)

Chromosome 4 - NC_133179.1Genomic Context describing neighboring genes Neighboring gene microRNA 430b-10 Neighboring gene uncharacterized LOC141381786 Neighboring gene microRNA 430b-9 Neighboring gene uncharacterized LOC141381778

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Ythdf m(6)A Readers Function Redundantly during Zebrafish Development. Kontur C, et al. Cell Rep, 2020 Dec 29. PMID 33378672, Free PMC Article
  2. Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan. Liu Y, et al. Front Genet, 2020. PMID 32849832, Free PMC Article
  3. Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization. D'Orazio FM, et al. Dev Cell, 2021 Mar 8. PMID 33651978, Free PMC Article
  4. Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation. Chan SH, et al. Dev Cell, 2019 Jun 17. PMID 31211993, Free PMC Article
  5. The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation. Miao L, et al. Mol Cell, 2022 Mar 3. PMID 35182480, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Other Names

  • miR-430a-18

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039293.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JBMGRA010000004

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133179.1 Reference GRCz12tu Primary Assembly

    Range
    31612592..31612681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_034247.1: Suppressed sequence

    Description
    NR_034247.1: This RefSeq was permanently suppressed because it was defined based on the wrong location for this GeneID.
Nucleotide Protein Strain
Heading Accession and Version

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