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USP49 ubiquitin specific peptidase 49 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100030401, updated on 3-Apr-2024

Summary

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Gene symbol
USP49
Gene description
ubiquitin specific peptidase 49
See related
Ensembl:ENSMODG00000012836
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See USP49 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 2 NC_077228.1 (283689159..283855542, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 2 NC_008802.1 (284867540..284935766, complement)

Chromosome 2 - NC_077228.1Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene prickle planar cell polarity protein 4 Neighboring gene translocase of outer mitochondrial membrane 6 Neighboring gene uncharacterized LOC103103113 Neighboring gene heat shock cognate 71 kDa protein-like Neighboring gene mediator complex subunit 20 Neighboring gene bystin like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 49

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077228.1 Reference mMonDom1.pri

    Range
    283689159..283855542 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056818218.1 → XP_056674196.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  2. XM_056818217.1 → XP_056674195.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  3. XM_056818214.1 → XP_056674192.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  4. XM_056818227.1 → XP_056674205.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X2

  5. XM_056818216.1 → XP_056674194.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  6. XM_056818219.1 → XP_056674197.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  7. XM_056818213.1 → XP_056674191.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  8. XM_056818215.1 → XP_056674193.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  9. XM_056818222.1 → XP_056674200.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  10. XM_056818220.1 → XP_056674198.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  11. XM_056818221.1 → XP_056674199.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  12. XM_056818224.1 → XP_056674202.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  13. XM_056818225.1 → XP_056674203.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  14. XM_056818226.1 → XP_056674204.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    F7DCJ7

  15. XM_016431059.2 → XP_016286545.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    UniProtKB/TrEMBL
    A0A5F8H9K9, F7DCJ7
    Conserved Domains (4) summary
    cl02553
    Location:261 → 664
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:259 → 663
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:26 → 87
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    pfam11221
    Location:170 → 200
    Med21; Subunit 21 of Mediator complex

  16. XM_007483872.3 → XP_007483934.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    See identical proteins and their annotated locations for XP_007483934.1

    UniProtKB/TrEMBL
    A0A5F8H9K9, F7DCJ7
    Conserved Domains (4) summary
    cl02553
    Location:261 → 664
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:259 → 663
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:26 → 87
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    pfam11221
    Location:170 → 200
    Med21; Subunit 21 of Mediator complex

  17. XM_007483875.3 → XP_007483937.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    See identical proteins and their annotated locations for XP_007483937.1

    UniProtKB/TrEMBL
    A0A5F8H9K9, F7DCJ7
    Conserved Domains (4) summary
    cl02553
    Location:261 → 664
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:259 → 663
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:26 → 87
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    pfam11221
    Location:170 → 200
    Med21; Subunit 21 of Mediator complex

  18. XM_007483874.3 → XP_007483936.1  ubiquitin carboxyl-terminal hydrolase 49 isoform X1

    See identical proteins and their annotated locations for XP_007483936.1

    UniProtKB/TrEMBL
    A0A5F8H9K9, F7DCJ7
    Conserved Domains (4) summary
    cl02553
    Location:261 → 664
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:259 → 663
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:26 → 87
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    pfam11221
    Location:170 → 200
    Med21; Subunit 21 of Mediator complex
Nucleotide Protein
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