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FGFR2 fibroblast growth factor receptor 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009417, updated on 20-Feb-2025
Gene symbol
FGFR2
Gene description
fibroblast growth factor receptor 2
See related
Ensembl:ENSOCUG00000007069
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See FGFR2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 15 NC_091446.1 (9301522..9406504)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 18 NC_067391.1 (65340392..65444644, complement)

Chromosome 15 - NC_091446.1Genomic Context describing neighboring genes Neighboring gene arginyltransferase 1 Neighboring gene uncharacterized LOC138845280 Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene elongin-C pseudogene Neighboring gene uncharacterized LOC138845469

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cloning and sequencing of the rabbit FGFR2 cDNA. Yang ZW, et al. DNA Seq, 2000. PMID 11328652
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
fibroblast growth factor receptor 2
NP_001076157.1
XP_008268678.2
XP_008268679.2
XP_008268689.2
XP_069913096.1
XP_069913098.1
XP_069913099.1
XP_069913100.1
XP_069913101.1
XP_069913102.1
XP_069913103.1
XP_069913104.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082688.1 → NP_001076157.1  fibroblast growth factor receptor 2 precursor

    See identical proteins and their annotated locations for NP_001076157.1

    Status: PROVISIONAL

    Source sequence(s)
    AF184968
    UniProtKB/TrEMBL
    A0A5F9DN51, Q9TTZ3
    Conserved Domains (6) summary
    cd04973
    Location:47 → 124
    Ig1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:164 → 248
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:271 → 360
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    smart00410
    Location:263 → 359
    IG_like; Immunoglobulin like
    cd05101
    Location:456 → 768
    PTKc_FGFR2; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2
    pfam07714
    Location:481 → 757
    Pkinase_Tyr; Protein tyrosine kinase

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091446.1 Reference mOryCun1.1

    Range
    9301522..9406504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_070056997.1 → XP_069913098.1  fibroblast growth factor receptor 2 isoform X4

    UniProtKB/TrEMBL
    G1SSB0

  2. XM_070056999.1 → XP_069913100.1  fibroblast growth factor receptor 2 isoform X4

    UniProtKB/TrEMBL
    G1SSB0

  3. XM_008270456.4 → XP_008268678.2  fibroblast growth factor receptor 2 isoform X2

    UniProtKB/TrEMBL
    G1SSB0

  4. XM_070056995.1 → XP_069913096.1  fibroblast growth factor receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F9DN51

  5. XM_008270457.4 → XP_008268679.2  fibroblast growth factor receptor 2 isoform X3

    UniProtKB/TrEMBL
    A0A5F9DN51

  6. XM_070057000.1 → XP_069913101.1  fibroblast growth factor receptor 2 isoform X6

    UniProtKB/TrEMBL
    A0A5F9D4M5

  7. XM_070057001.1 → XP_069913102.1  fibroblast growth factor receptor 2 isoform X7

    UniProtKB/TrEMBL
    A0A5F9D4M5

  8. XM_070057002.1 → XP_069913103.1  fibroblast growth factor receptor 2 isoform X8

    UniProtKB/TrEMBL
    A0A5F9CR83

  9. XM_070057003.1 → XP_069913104.1  fibroblast growth factor receptor 2 isoform X9

    UniProtKB/TrEMBL
    A0A5F9CR83

  10. XM_008270467.4 → XP_008268689.2  fibroblast growth factor receptor 2 isoform X10

    UniProtKB/TrEMBL
    A0A5F9CR83

  11. XM_070056998.1 → XP_069913099.1  fibroblast growth factor receptor 2 isoform X5

    UniProtKB/TrEMBL
    G1SSB0
Nucleotide Protein
Heading Accession and Version

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