PPP1CA protein phosphatase 1 catalytic subunit alpha [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: PPP1CA
Gene description: protein phosphatase 1 catalytic subunit alpha
See related: Ensembl:ENSOCUG00000027936
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as: PPP1A
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
: Try the new Gene page
Try the new Transcripts and proteins table

Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_11	current	mOryCun1.1 (GCF_964237555.1)	1	NC_091432.1 (4648090..4650540)
RS_2023_02	previous assembly	UM_NZW_1.0 (GCF_009806435.1)	1	NC_067374.1 (208553764..208556224, complement)

Chromosome 1 - NC_091432.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells.
Title: Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

Ppp1ca (e-PCR), detects polymorphism
- UniSTS:472882

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: serine/threonine-protein phosphatase PP1-alpha catalytic subunit

Names: PP-1A; protein phosphatase 1, catalytic subunit, alpha isozyme

NP_001095176.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101706.1 → NP_001095176.1 serine/threonine-protein phosphatase PP1-alpha catalytic subunit

See identical proteins and their annotated locations for NP_001095176.1

Status: PROVISIONAL

Source sequence(s)

Y00701

UniProtKB/TrEMBL

G1U3X6

Related

ENSOCUP00000024093.2, ENSOCUT00000030891.2

Conserved Domains (2) summary

smart00156
Location:11 → 280

PP2Ac; Protein phosphatase 2A homologues, catalytic domain

cd07414
Location:11 → 279

MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain