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CRYAB crystallin alpha B [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009295, updated on 20-Feb-2025
Gene symbol
CRYAB
Gene description
crystallin alpha B
See related
Ensembl:ENSOCUG00000012972
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See CRYAB in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 1 NC_091432.1 (103864558..103880209, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 1 NC_067374.1 (118414404..118417357)

Chromosome 1 - NC_091432.1Genomic Context describing neighboring genes Neighboring gene ALG9 alpha-1,2-mannosyltransferase Neighboring gene ferredoxin-fold anticodon binding domain containing 1 Neighboring gene cilia and flagella associated protein 68 Neighboring gene chromosome 1 C11orf52 homolog Neighboring gene alpha-endosulfine pseudogene Neighboring gene heat shock protein family B (small) member 2 Neighboring gene DIX domain containing 1 Neighboring gene uncharacterized LOC127483215 Neighboring gene dihydrolipoamide S-acetyltransferase

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Expression of Crystallins, Pax6, Filensin, CP49, MIP, and MP20 in lens-derived cell lines. Krausz E, et al. Invest Ophthalmol Vis Sci, 1996 Sep. PMID 8814151
  2. Primary structure of rabbit lens alpha-crystallins. Parveen R, et al. J Protein Chem, 1993 Feb. PMID 8427639
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables structural constituent of eye lens IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein refolding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to heat IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
alpha-crystallin B chain
Names
HspB5 protein
alpha-B-crystallin

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082407.1 → NP_001075876.1  alpha-crystallin B chain

    See identical proteins and their annotated locations for NP_001075876.1

    Status: PROVISIONAL

    Source sequence(s)
    X95383
    UniProtKB/Swiss-Prot
    P41316
    Related
    ENSOCUP00000011163.3, ENSOCUT00000012969.3
    Conserved Domains (3) summary
    cd06498
    Location:67 → 150
    ACD_alphaB-crystallin_HspB5; Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaB-crystallin (HspB5, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers ...
    COG0071
    Location:11 → 161
    IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]
    pfam00525
    Location:1 → 51
    Crystallin; Alpha crystallin A chain, N terminal

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091432.1 Reference mOryCun1.1

    Range
    103864558..103880209 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_070070454.1 → XP_069926555.1  alpha-crystallin B chain isoform X1

    UniProtKB/Swiss-Prot
    P41316

  2. XM_070070510.1 → XP_069926611.1  alpha-crystallin B chain isoform X1

    UniProtKB/Swiss-Prot
    P41316

  3. XM_070070588.1 → XP_069926689.1  alpha-crystallin B chain isoform X1

    UniProtKB/Swiss-Prot
    P41316

  4. XM_070070477.1 → XP_069926578.1  alpha-crystallin B chain isoform X1

    UniProtKB/Swiss-Prot
    P41316
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41316.1 GenPept UniProtKB/Swiss-Prot:P41316

Gene LinkOut

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