LDHA lactate dehydrogenase A [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: LDHA
Gene description: lactate dehydrogenase A
See related: Ensembl:ENSOCUG00000015939
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as: LDH-M
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_11	current	mOryCun1.1 (GCF_964237555.1)	1	NC_091432.1 (48002398..48014276, complement)
RS_2023_02	previous assembly	UM_NZW_1.0 (GCF_009806435.1)	Unplaced Scaffold	NW_026257081.1 (30835..42735)

Chromosome 1 - NC_091432.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Dynamic changes of LDH and HBDH activities may be useful in diagnosis of non-thermal low voltage electrical injury and in estimation of post injury intervals.
Title: [Dynamic changes of LDH and HBDH activity in rabbit serum after low voltage electrical injury].

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables L-lactate dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in lactate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in pyruvate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: L-lactate dehydrogenase A chain

Names: LDH muscle subunit; LDH-A; lactate dehydrogenase-M

NP_001075746.1

EC 1.1.1.27

XP_008273294.1

EC 1.1.1.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082277.1 → NP_001075746.1 L-lactate dehydrogenase A chain

See identical proteins and their annotated locations for NP_001075746.1

Status: PROVISIONAL

Source sequence(s)

M22585

UniProtKB/Swiss-Prot

P13491

UniProtKB/TrEMBL

G1TX67

Related

ENSOCUP00000021667.2, ENSOCUT00000025209.2

Conserved Domains (1) summary

cd05293
Location:19 → 329

LDH_1; A subgroup of L-lactate dehydrogenases

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

NC_091432.1 Reference mOryCun1.1

Range

48002398..48014276 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008275072.4 → XP_008273294.1 L-lactate dehydrogenase A chain isoform X1

UniProtKB/TrEMBL

A0A5F9D4H9

Related

ENSOCUP00000040783.1

Conserved Domains (2) summary

cd05293
Location:48 → 358

LDH_1; A subgroup of L-lactate dehydrogenases

TIGR01771
Location:54 → 353

L-LDH-NAD; L-lactate dehydrogenase