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ALDOA aldolase, fructose-bisphosphate A [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100009055, updated on 5-Sep-2025
Gene symbol
ALDOA
Gene description
aldolase, fructose-bisphosphate A
See related
Ensembl:ENSOCUG00000006329
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
all
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See ALDOA in Genome Data Viewer
Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 19 NC_091450.1 (7439075..7444486)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 6 NC_067379.1 (18435655..18440976)

Chromosome 19 - NC_091450.1Genomic Context describing neighboring genes Neighboring gene fertilization-influencing membrane protein 1 Neighboring gene TLC domain containing 3B Neighboring gene uncharacterized LOC108176793 Neighboring gene protein phosphatase 4 catalytic subunit Neighboring gene T-box transcription factor 6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The complete nucleotide sequence for rabbit muscle aldolase A messenger RNA. Tolan DR, et al. J Biol Chem, 1984 Jan 25. PMID 6546378
  2. Affinity labeling of a previously undetected essential lysyl residue in class I fructose bisphosphate aldolase. Hartman FC, et al. J Biol Chem, 1976 May 25. PMID 5453
  3. Identification of the C-1-phosphate-binding arginine residue of rabbit-muscle aldolase. Isolation of 1,2-cyclohexanedione-labeled peptide by chemisorption chromatography. Patthy L, et al. Eur J Biochem, 1979 Sep. PMID 499203
  4. Extended amino acid sequences around the active-site lysine residue of class-I fructose 1,6-bisphosphate aldolases from rabbit muscle, sturgeon muscle, trout muscle and ox liver. Benfield PA, et al. Biochem J, 1979 Nov 1. PMID 534504, Free PMC Article
  5. Studies on the structure of rabbit muscle aldolase. Ordering of the tryptic peptides; sequence of 164 amino acid residues in the NH2-terminal BrCN peptide. Nakai N, et al. Arch Biochem Biophys, 1975 Jan. PMID 1122141

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The lattice of muscle aldolase contacts corresponded to an increased number of interactions between high-entropy side chains that mitigate the lattice strain incurred upon cryocooling and accompanying mosaic spread increases.
    Title: Dramatic improvement of crystal quality for low-temperature-grown rabbit muscle aldolase.
  2. kinetic and structural analyses of fructose-bisphosphate aldolase
    Title: Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fructose-bisphosphate aldolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 1,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
fructose-bisphosphate aldolase A
Names
aldolase A, fructose-bisphosphate
muscle-type aldolase
NP_001075707.1
XP_008256151.1
XP_008256152.1
XP_017197924.1
XP_069919826.1
XP_069919827.1
XP_069919828.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082238.1 → NP_001075707.1  fructose-bisphosphate aldolase A

    See identical proteins and their annotated locations for NP_001075707.1

    Status: VALIDATED

    Source sequence(s)
    K02300
    UniProtKB/Swiss-Prot
    P00883, Q28671
    Conserved Domains (1) summary
    pfam00274
    Location:15 → 364
    Glycolytic; Fructose-bisphosphate aldolase class-I

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091450.1 Reference mOryCun1.1

    Range
    7439075..7444486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_070063726.1 → XP_069919827.1  fructose-bisphosphate aldolase A isoform X1

    UniProtKB/TrEMBL
    A0A5F9D5U7

  2. XM_008257930.4 → XP_008256152.1  fructose-bisphosphate aldolase A isoform X2

    See identical proteins and their annotated locations for XP_008256152.1

    UniProtKB/Swiss-Prot
    P00883, Q28671
    Conserved Domains (1) summary
    pfam00274
    Location:15 → 364
    Glycolytic; Fructose-bisphosphate aldolase class-I

  3. XM_017342435.3 → XP_017197924.1  fructose-bisphosphate aldolase A isoform X2

    UniProtKB/Swiss-Prot
    P00883, Q28671
    Related
    ENSOCUP00000008499.2
    Conserved Domains (1) summary
    pfam00274
    Location:15 → 364
    Glycolytic; Fructose-bisphosphate aldolase class-I

  4. XM_008257929.4 → XP_008256151.1  fructose-bisphosphate aldolase A isoform X2

    See identical proteins and their annotated locations for XP_008256151.1

    UniProtKB/Swiss-Prot
    P00883, Q28671
    Conserved Domains (1) summary
    pfam00274
    Location:15 → 364
    Glycolytic; Fructose-bisphosphate aldolase class-I

  5. XM_070063725.1 → XP_069919826.1  fructose-bisphosphate aldolase A isoform X1

    UniProtKB/TrEMBL
    A0A5F9D5U7

  6. XM_070063727.1 → XP_069919828.1  fructose-bisphosphate aldolase A isoform X2

    UniProtKB/Swiss-Prot
    P00883, Q28671
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00883.2 GenPept UniProtKB/Swiss-Prot:P00883

Gene LinkOut

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