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PYGM glycogen phosphorylase, muscle associated [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100008972, updated on 5-Sep-2025
Gene symbol
PYGM
Gene description
glycogen phosphorylase, muscle associated
See related
Ensembl:ENSOCUG00000002173
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
all
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See PYGM in Genome Data Viewer
Location:
chromosome: 1
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 1 NC_091432.1 (6717392..6727802)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026258873.1 (15684..25973)

Chromosome 1 - NC_091432.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 2 Neighboring gene splicing factor 1 Neighboring gene RAS guanyl releasing protein 2 Neighboring gene neurexin 2 Neighboring gene uncharacterized LOC138848588

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The binding of 2-deoxy-D-glucose 6-phosphate to glycogen phosphorylase b: kinetic and crystallographic studies. Oikonomakos NG, et al. J Mol Biol, 1995 Dec 15. PMID 7500360
  2. Sequence of the carboxyl-terminal 492 residues of rabbit muscle glycogen phosphorylase including the pyridoxal 5'-phosphate binding site. Titani K, et al. Biochemistry, 1978 Dec 26. PMID 728426
  3. Crystallographic analysis of phosphorylase alpha at 2.5 A resolution, a comment on the chemical sequence. Sprang S, et al. Biochemistry, 1978 Dec 26. PMID 728427
  4. Assignment of the amino acid sequence to the crystal structure of glycogen phosphorylase b. Jenkins JA, et al. Biochemistry, 1978 Dec 26. PMID 728428
  5. Domain separation in the activation of glycogen phosphorylase a. Goldsmith EJ, et al. Science, 1989 Aug 4. PMID 2756432

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Effect of arginine on stability and aggregation of muscle glycogen phosphorylase b.
    Title: Effect of arginine on stability and aggregation of muscle glycogen phosphorylase b.
  2. These results suggest that some conformational changes have taken place in the maltooligosaccharide-binding region of the GP catalytic site during allosteric regulation.
    Title: Probing the catalytic site of rabbit muscle glycogen phosphorylase using a series of specifically modified maltohexaose derivatives.
  3. The formation of a complex between the denatured monomeric form of Phb and the dissociated forms of GroEL is detected during heating at 46 degrees C.
    Title: Effect of GroEL on thermal aggregation of glycogen phosphorylase b from rabbit skeletal muscle.
  4. alpha-crystallin interacts with the intermediates of unfolding of the Phb molecule
    Title: Kinetics of thermal aggregation of glycogen phosphorylase b from rabbit skeletal muscle: mechanism of protective action of alpha-crystallin.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glycogen phosphorylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycogen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
glycogen phosphorylase, muscle form
Names
myophosphorylase
phosphorylase, glycogen, muscle
NP_001075653.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082184.1 → NP_001075653.1  glycogen phosphorylase, muscle form

    See identical proteins and their annotated locations for NP_001075653.1

    Status: PROVISIONAL

    Source sequence(s)
    X04265
    UniProtKB/Swiss-Prot
    P00489
    UniProtKB/TrEMBL
    B7NZI0
    Related
    ENSOCUP00000001880.3, ENSOCUT00000002177.3
    Conserved Domains (2) summary
    cd04300
    Location:29 → 828
    GT1_Glycogen_Phosphorylase; This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of ...
    TIGR02093
    Location:32 → 828
    P_ylase; glycogen/starch/alpha-glucan phosphorylases

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091432.1 Reference mOryCun1.1

    Range
    6717392..6727802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00489.3 GenPept UniProtKB/Swiss-Prot:P00489

Gene LinkOut

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