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INSR insulin receptor [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100008911, updated on 17-Dec-2024
Gene symbol
INSR
Gene description
insulin receptor
See related
Ensembl:ENSOCUG00000004436
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
DAF-2
Orthologs
human mouse all
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See INSR in Genome Data Viewer
Location:
chromosome: 16
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 16 Unlocalized Scaffold NW_027208201.1 (3559319..3698766, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259210.1 (1074670..1213047)

NW_027208201.1Genomic Context describing neighboring genes Neighboring gene vomeronasal type-2 receptor 116-like Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like Neighboring gene glutamic acid-rich protein-like Neighboring gene Rho/Rac guanine nucleotide exchange factor 18 Neighboring gene peroxisomal biogenesis factor 11 gamma

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cell lineage-specific signaling of insulin and insulin-like growth factor I in rabbit blastocysts. Navarrete Santos A, et al. Endocrinology, 2008 Feb. PMID 17962341
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor substrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of insulin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
insulin receptor

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RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NW_027208201.1 Reference mOryCun1.1

    Range
    3559319..3698766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017337975.3 → XP_017193464.2  insulin receptor isoform X4

    UniProtKB/TrEMBL
    G1U0V9

  2. XM_017337974.3 → XP_017193463.2  insulin receptor isoform X3

    UniProtKB/TrEMBL
    G1U0V9

  3. XM_017337973.3 → XP_017193462.2  insulin receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DAH8

  4. XM_008249177.4 → XP_008247399.2  insulin receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DAH8
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials