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NR3C1 nuclear receptor subfamily 3 group C member 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100008890, updated on 5-Sep-2025
Gene symbol
NR3C1
Gene description
nuclear receptor subfamily 3 group C member 1
See related
Ensembl:ENSOCUG00000011676
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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See NR3C1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_11 current mOryCun1.1 (GCF_964237555.1) 6 NC_091437.1 (30743854..30877460, complement)
RS_2023_02 previous assembly UM_NZW_1.0 (GCF_009806435.1) 3 NC_067376.1 (25146736..25251890, complement)

Chromosome 6 - NC_091437.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 26 Neighboring gene uncharacterized LOC127490692 Neighboring gene uncharacterized LOC138850173 Neighboring gene uncharacterized LOC138850174 Neighboring gene collagen, type I, alpha 1b-like Neighboring gene uncharacterized LOC103347906 Neighboring gene U6 spliceosomal RNA

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Presence of a transcriptionally active glucocorticoid receptor alpha in lens epithelial cells. James ER, et al. Invest Ophthalmol Vis Sci, 2003 Dec. PMID 14638726
  2. Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation. Dittmar KD, et al. J Biol Chem, 1997 May 16. PMID 9148915
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estrogen response element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear glucocorticoid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear receptor-mediated glucocorticoid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
glucocorticoid receptor
Names
GR
glucocorticoid receptor alpha
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NP_001075616.1

Length

  • 772

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082147.1 → NP_001075616.1  glucocorticoid receptor

    See identical proteins and their annotated locations for NP_001075616.1

    Status: PROVISIONAL

    Source sequence(s)
    AY161275
    UniProtKB/Swiss-Prot
    P59667
    UniProtKB/TrEMBL
    A0A5F9DMK9
    Related
    ENSOCUP00000040701.1, ENSOCUT00000054032.1
    Conserved Domains (3) summary
    cd07076
    Location:526 → 772
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:412 → 489
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:28 → 397
    GCR; Glucocorticoid receptor

RefSeqs of Annotated Genomes: GCF_964237555.1-RS_2024_11

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOryCun1.1

Genomic

  1. NC_091437.1 Reference mOryCun1.1

    Range
    30743854..30877460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_070074975.1 → XP_069931076.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  2. XM_070074969.1 → XP_069931070.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  3. XM_070074973.1 → XP_069931074.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  4. XM_008254834.4 → XP_008253056.2  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  5. XM_070074972.1 → XP_069931073.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  6. XM_008254835.4 → XP_008253057.2  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  7. XM_070074971.1 → XP_069931072.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  8. XM_051843243.2 → XP_051699203.2  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  9. XM_070074976.1 → XP_069931077.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  10. XM_051843245.2 → XP_051699205.2  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  11. XM_008254837.4 → XP_008253059.2  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  12. XM_008254832.4 → XP_008253054.2  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  13. XM_070074974.1 → XP_069931075.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9

  14. XM_051843244.2 → XP_051699204.2  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  15. XM_070074970.1 → XP_069931071.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    A0A5F9DMK9

  16. XM_070074977.1 → XP_069931078.1  glucocorticoid receptor isoform X2

    UniProtKB/TrEMBL
    A0A5F9DMK9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P59667.1 GenPept UniProtKB/Swiss-Prot:P59667

Gene LinkOut

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Research Materials