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a2ml alpha-2-macroglobulin-like [ Danio rerio (zebrafish) ]

Gene ID: 100006972, updated on 7-Jan-2019

Summary

Official Symbol
a2mlprovided by ZNC
Official Full Name
alpha-2-macroglobulin-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090212-1
See related
Ensembl:ENSDARG00000041645 Ensembl:ENSDARG00000056314
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio

Genomic context

See a2ml in Genome Data Viewer
Location:
chromosome: 15
Exon count:
68
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (21113965..21155671, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (21178237..21196748, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene si:ch211-212c13.10 Neighboring gene si:dkey-52d15.2 Neighboring gene alpha-2-macroglobulin-like Neighboring gene alpha-2-macroglobulin-like

Genomic regions, transcripts, and products

Bibliography

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
liver development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001139479.1NP_001132951.1  alpha-2-macroglobulin-like precursor

    See identical proteins and their annotated locations for NP_001132951.1

    Status: PROVISIONAL

    Source sequence(s)
    EU689051
    UniProtKB/TrEMBL
    B8QSI4
    Related
    ENSDARP00000073195.4, ENSDART00000078734.6
    Conserved Domains (6) summary
    cd02897
    Location:9481234
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:729817
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:127218
    A2M_N; MG2 domain
    pfam07677
    Location:13411431
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:10001236
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:466607
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    21113965..21155671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481320.1XP_021336995.1  alpha-2-macroglobulin-like isoform X1

    Conserved Domains (5) summary
    cd02897
    Location:9551241
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:736824
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:134225
    A2M_N; MG2 domain
    pfam07677
    Location:13481438
    A2M_recep; A-macroglobulin receptor
    pfam07703
    Location:466616
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
  2. XM_001345505.8XP_001345541.6  alpha-2-macroglobulin-like isoform X2

    Related
    ENSDARP00000046442.6, ENSDART00000046443.7
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