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ercc6l excision repair cross-complementation group 6-like [ Danio rerio (zebrafish) ]

Gene ID: 100005291, updated on 9-Sep-2025
Official Symbol
ercc6lprovided by ZNC
Official Full Name
excision repair cross-complementation group 6-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060531-56
See related
Ensembl:ENSDARG00000002479 AllianceGenome:ZFIN:ZDB-GENE-060531-56
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-278b8.3
Summary
Predicted to enable DNA translocase activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within cell division and intein-mediated protein splicing. Predicted to be located in kinetochore. Orthologous to human ERCC6L (ERCC excision repair 6 like, spindle assembly checkpoint helicase). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See ercc6l in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 5 NC_133180.1 (24592669..24605094)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 5 NC_007116.7 (23913660..23926253)

Chromosome 5 - NC_133180.1Genomic Context describing neighboring genes Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 Neighboring gene uncharacterized LOC101885710 Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 6 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1a Neighboring gene MAP7 domain containing 2a Neighboring gene eukaryotic translation initiation factor 1A X-linked a

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Foxm1 regulates cardiomyocyte proliferation in adult zebrafish after cardiac injury. Zuppo DA, et al. Development, 2023 Mar 15. PMID 36846912, Free PMC Article
  2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent chromatin remodeler activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA translocase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within intein-mediated protein splicing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA excision repair protein ERCC-6-like
Names
ATP-dependent helicase ERCC6-like
excision repair cross-complementing rodent repair deficiency, complementation group 6-like

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100093.3 → NP_001093563.2  DNA excision repair protein ERCC-6-like

    Status: VALIDATED

    Source sequence(s)
    JBMGRA010000005
    Related
    ENSDARP00000012447.6, ENSDART00000015401.7

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133180.1 Reference GRCz12tu Primary Assembly

    Range
    24592669..24605094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2BGR3.1 GenPept UniProtKB/Swiss-Prot:A2BGR3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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