rilpl2 Rab interacting lysosomal protein-like 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rilpl2provided by ZNC
Official Full Name: Rab interacting lysosomal protein-like 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6682
See related: Ensembl:ENSDARG00000024818 AllianceGenome:ZFIN:ZDB-GENE-030131-6682
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa02e07; wu:fa02e07; zgc:162589
Summary: Predicted to enable protein dimerization activity. Predicted to be involved in cilium assembly; epithelial cell morphogenesis; and protein transport from ciliary membrane to plasma membrane. Predicted to act upstream of or within protein transport. Predicted to be located in centrosome and cilium. Predicted to be active in ciliary basal body and cytoplasm. Orthologous to human RILPL2 (Rab interacting lysosomal protein like 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (69795198..69804450, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (69022648..69031911, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables dynein light intermediate chain binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables small GTPase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in epithelial cell morphogenesis	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in protein transport from ciliary membrane to plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ciliary basal body	IBA Inferred from Biological aspect of Ancestor more info
located_in cilium	IEA Inferred from Electronic Annotation more info
located_in cilium	ISS Inferred from Sequence or Structural Similarity more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RILP-like protein 2

Names: rab-interacting lysosomal-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001083850.1 → NP_001077319.1 RILP-like protein 2

See identical proteins and their annotated locations for NP_001077319.1

Status: PROVISIONAL

Source sequence(s)

BC135027

UniProtKB/Swiss-Prot

A4IGC3, A5WUX4

UniProtKB/TrEMBL

A0A2R8PWJ3

Related

ENSDARP00000030815.5, ENSDART00000028954.7

Conserved Domains (2) summary

cd14445
Location:8 → 92

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

pfam11461
Location:120 → 176

RILP; Rab interacting lysosomal protein

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

69795198..69804450 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005168657.4 → XP_005168714.1 RILP-like protein 2 isoform X1

UniProtKB/Swiss-Prot

A4IGC3, A5WUX4

UniProtKB/TrEMBL

A0A8M2BFX9

Conserved Domains (2) summary

cd14445
Location:8 → 92

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

pfam11461
Location:121 → 181

RILP; Rab interacting lysosomal protein