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abl1 c-abl oncogene 1, non-receptor tyrosine kinase [ Danio rerio (zebrafish) ]

Gene ID: 100000720, updated on 4-Aug-2017
Official Symbol
abl1provided by ZNC
Official Full Name
c-abl oncogene 1, non-receptor tyrosine kinaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-100812-9
See related
Ensembl:ENSDARG00000035187 Vega:OTTDARG00000034046
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Orthologs
Location:
chromosome: 5
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (72144658..72169569)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (71360153..71384745)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene sepiapterin reductase a Neighboring gene exosome component 2 Neighboring gene RAB14, member RAS oncogene family, like Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 54

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
peptidyl-tyrosine autophosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
extrinsic component of cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
tyrosine-protein kinase ABL1
Names
c-abl oncogene 1, receptor tyrosine kinase
XP_005172104.1
XP_005172105.1

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    72144658..72169569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005172047.4XP_005172104.1  tyrosine-protein kinase ABL1 isoform X1

    UniProtKB/TrEMBL
    F8W2F9
    Related
    ENSDARP00000124744.1, OTTDARP00000037700
    Conserved Domains (5) summary
    smart00808
    Location:9581081
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:137230
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:79132
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:249511
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:256507
    Pkinase_Tyr; Protein tyrosine kinase
  2. XM_005172048.4XP_005172105.1  tyrosine-protein kinase ABL1 isoform X2

    Related
    ENSDARP00000125008.1, OTTDARP00000037701
    Conserved Domains (5) summary
    smart00808
    Location:9411064
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:120213
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:62115
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:232494
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
    pfam07714
    Location:239490
    Pkinase_Tyr; Protein tyrosine kinase
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