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Il17f interleukin 17F [ Mus musculus (house mouse) ]

Gene ID: 257630, updated on 23-Nov-2021

Summary

Official Symbol
Il17fprovided by MGI
Official Full Name
interleukin 17Fprovided by MGI
Primary source
MGI:MGI:2676631
See related
Ensembl:ENSMUSG00000041872
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C87042; IL-17F
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Il17f in Genome Data Viewer
Location:
1; 1 A4
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (20847370..20855498, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (20777146..20785274, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (20767227..20774351, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA of muscle differentiation 1 Neighboring gene microRNA 133b Neighboring gene interleukin 17A Neighboring gene minichromosome maintenance complex component 3 Neighboring gene chaperonin containing Tcp1, subunit 7 (eta) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (8)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity ISO
Inferred from Sequence Orthology
more info
 
enables cytokine binding ISO
Inferred from Sequence Orthology
more info
 
enables cytokine receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein heterodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in cartilage development ISO
Inferred from Sequence Orthology
more info
 
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in defense response to Gram-positive bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in interleukin-17-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of antimicrobial peptide production IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of chemokine (C-X-C motif) ligand 1 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cytokine production ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of cytokine production involved in inflammatory response IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of cytokine production involved in inflammatory response IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of interleukin-6 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of lymphotoxin A production ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of granulocyte macrophage colony-stimulating factor production ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of interleukin-2 production ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of interleukin-8 production ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transforming growth factor beta receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145856.2NP_665855.2  interleukin-17F precursor

    See identical proteins and their annotated locations for NP_665855.2

    Status: VALIDATED

    Source sequence(s)
    AC159614
    Consensus CDS
    CCDS35522.1
    UniProtKB/Swiss-Prot
    Q7TNI7
    Related
    ENSMUSP00000046960.4, ENSMUST00000039046.10
    Conserved Domains (1) summary
    pfam06083
    Location:78152
    IL17; Interleukin-17

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    20847370..20855498 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006495523.2XP_006495586.1  interleukin-17F isoform X1

    See identical proteins and their annotated locations for XP_006495586.1

    UniProtKB/Swiss-Prot
    Q7TNI7
    Related
    ENSMUSP00000140122.2, ENSMUST00000189301.2
    Conserved Domains (1) summary
    pfam06083
    Location:78152
    IL17; Interleukin-17
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