Format

Send to:

Choose Destination

Il13 interleukin 13 [ Mus musculus (house mouse) ]

Gene ID: 16163, updated on 23-Nov-2021

Summary

Official Symbol
Il13provided by MGI
Official Full Name
interleukin 13provided by MGI
Primary source
MGI:MGI:96541
See related
Ensembl:ENSMUSG00000020383
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Il-13
Expression
Biased expression in thymus adult (RPKM 2.8), testis adult (RPKM 0.6) and 2 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Il13 in Genome Data Viewer
Location:
11 B1.3; 11 31.98 cM
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (53522150..53525529, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (53631323..53634702, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (53444825..53448204, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A430108G06 gene Neighboring gene kinesin family member 3A Neighboring gene origin of replication in Il13 Neighboring gene interleukin 4 Neighboring gene ribosomal protein S2, pseudogene 4 Neighboring gene Th2 cytokine locus control region Neighboring gene RAD50 double strand break repair protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 
enables interleukin-13 receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to cytokine stimulus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in macrophage activation ISO
Inferred from Sequence Orthology
more info
 
involved_in microglial cell activation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of NAD(P)H oxidase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of complement-dependent cytotoxicity ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of endothelial cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of inflammatory response ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of neuron death ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of transforming growth factor beta production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of B cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cold-induced thermogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of connective tissue growth factor production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of immunoglobulin production IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within positive regulation of immunoglobulin production IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of immunoglobulin production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of interleukin-10 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of macrophage activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of mast cell degranulation IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within positive regulation of mast cell degranulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of pancreatic stellate cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of tyrosine phosphorylation of STAT protein ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of proton transport ISO
Inferred from Sequence Orthology
more info
 
involved_in response to nicotine ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
interleukin-13
Names
T-cell activation protein P600

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008355.3NP_032381.1  interleukin-13 precursor

    See identical proteins and their annotated locations for NP_032381.1

    Status: VALIDATED

    Source sequence(s)
    AA646049, M23504
    Consensus CDS
    CCDS24683.1
    UniProtKB/Swiss-Prot
    P20109
    Related
    ENSMUSP00000020650.2, ENSMUST00000020650.2
    Conserved Domains (1) summary
    pfam03487
    Location:21130
    IL13; Interleukin-13

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    53522150..53525529 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center