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Items: 1 to 20 of 61401

1.
Full record GDS5657

Transcription factor Cabut deficiency and overexpression effects on heads: time course

Analysis of heads from strains overexpressing Cabut (cbtOE) or depleted for Cabut (cbtRNAi) at two time points during the day-night cycle (i.e., 3 hr after light-on or light-off). Krüppel‐like factors Klf10 and Klf11 are close mammalian homologs of cbt. Results provide insight into role of CBT.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 3 genotype/variation, 2 time sets
Platform:
GPL1322
Series:
GSE67865
6 Samples
Download data: CEL
2.
Full record GDS4611

Ionizing radiation effect on p53 mutant third instar larvae wing imaginal discs: time course

Analysis of p53 mutant larvae wing imaginal discs up to 18hr after exposure to ionizing radiation (IR). Results provide insight into the molecular mechanisms underlying IR-induced, p53-independent apoptosis in larvae.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol, 2 time sets
Platform:
GPL1322
Series:
GSE37404
16 Samples
Download data: CEL
3.
Full record GDS4499

Larval brains and imaginal discs with centrosome loss or amplification

Analysis of 3rd instar larval brains and imaginal discs that lack centrosomes (DSas-4 and DSas-6) or have too many centrosomes (SakOE). Centrosome defects are common to many cancers. Results provide insight into the effects of centrosome loss or amplification on cell physiology.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 3 genotype/variation, 5 strain sets
Platform:
GPL1322
Series:
GSE35240
15 Samples
Download data: CEL
4.
Full record GDS4496

Wing disc response to Epidermal Growth Factor Receptor signaling perturbations

Analysis of third instar wing disc from EGFR dominant negative (71B-Gal4; UAS EgfrDN) and EGFR activated (71B-GAL4; UAS EgfrACT) larvae. Aberrant signaling of highly conserved EGFR pathway is implicated in a number of diseases. Results provide insight into the identity of new EGFR-responsive genes.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL72
Series:
GSE34872
6 Samples
Download data: CEL
5.
Full record GDS4494

Segmental monosomy

Analysis of adult females representing segmental deficiencies (Df), both as single Df/+ genotypes and in pairwise Df combinations. Aneuploidies such as segmental monosomy are associated with developmental abnormalities. Results provide insight into the effects of aneuploidies on the transcriptome.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 27 genotype/variation, 8 other sets
Platform:
GPL1322
Series:
GSE34400
44 Samples
Download data: CEL
6.
Full record GDS4438

Phagocytic receptor Eater depleted hemocyte-derived cell line response to phagocytosed bacteria: time course

Analysis of phagocytic receptor Eater depleted hemocyte-derived S2 cells after phagocytosing bacteria for up to 180 minutes. Results provide insight into the role of Eater in the transcriptional regulation of genes that are induced after bacterial binding and phagocytosis.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation, 3 time sets
Platform:
GPL1322
Series:
GSE31564
24 Samples
Download data: CEL
7.
Full record GDS4201

Chronic hypoxia effect on dmDys model of Duchenne Muscular Dystrophy: single whole animal

Analysis of 3-5 day-old dystrophin-deficient animals exposed to chronic hypoxia (CH) for 2 weeks. Respiratory muscle necrosis in late-stage DMD is associated with respiratory insufficiency and CH. Results provide insight into the effects of CH on dystrophin-deficient muscle in vivo.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 strain, 3 stress sets
Platform:
GPL1322
Series:
GSE15879
16 Samples
Download data: CEL, CHP
8.
Full record GDS3871

Male and female genital imaginal discs during early morphogenesis: time course

Analysis of female or male genital discs dissected during early morphogenesis (L3, P6, or P20). In flies, the sex-determination hierarchy terminates in the doublesex (dsx) gene. Results provide insight into molecular mechanisms downstream of dsx underlying sex-specific differentiation of genitalia.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 3 development stage, 2 gender sets
Platform:
GPL1322
Series:
GSE23344
24 Samples
Download data: CEL
DataSet
Accession:
GDS3871
ID:
3871
9.
Full record GDS3854

Early neuronal development: embryos

Analysis of atonal-expressing (atoGFP+) and atoGFP- cells from transgenic wild type and ato-mutant embryos, at 3 time points corresponding to the first 3hr of neural development. Results provide insight into how proneural factors such as ato regulate specialized neuronal differentiation pathways.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 2 cell type, 3 development stage, 2 genotype/variation sets
Platform:
GPL1322
Series:
GSE21520
31 Samples
Download data: CEL
10.
Full record GDS3835

Drosophila development: parental species and interspecific hybrids

Analysis of males of 3 species (melanogaster, sechellia, simulans) and D. sechellia x D. simulans F1 hybrids during 4 developmental stages. Results within and between pure species and hybrids provide insight into both the evolution of gene regulation in the context of development and speciation.
Organism:
Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans
Type:
Expression profiling by array, log2 ratio, 4 development stage, 4 species sets
Platform:
GPL3598
Series:
GSE17535
48 Samples
Download data
11.
Full record GDS3707

Acute ethanol exposure: time course

Analysis of heads of animals exposed to ethanol vapor for up to 240 minutes. Increased ethanol intake is facilitated by the development of tolerance to the aversive and pleasurable effects of ethanol. Results provide insight into the molecular mechanisms underlying ethanol tolerance development.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 3 agent, 8 time sets
Platform:
GPL1322
Series:
GSE18208
16 Samples
Download data: CEL
12.
Full record GDS3639

Male and female fruit flies of various wild-type laboratory strains

Analysis of male and female flies of 5 wild-type laboratory strains. Results provide insight into the extent to which transcriptional variation is inherent in commonly used laboratory strains and the relationship of variation in gene expression to sexual dimorphism.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 2 gender, 5 strain sets
Platform:
GPL72
Series:
GSE9149
29 Samples
Download data: CEL
13.
Full record GDS3633

p24 deficiency

Analysis of abdominal and head/thorax segments of mutants lacking p24. Members of the p24 protein family are transmembrane constituents of the ER and Golgi-derived transport vesicles that function in trafficking secretory proteins. Results provide insight into the effect of the loss of p24 function.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 genotype/variation, 2 tissue sets
Platform:
GPL1322
Series:
GSE10940
12 Samples
Download data: CEL
14.
Full record GDS3477

Zinc finger protein Zelda deficiency effect on the embryo

Analysis of embryos lacking the zinc finger protein Zelda. Results provide insight into the role of Zelda in the transfer of control of embryogenesis to the zygotic genome during the process of maternal-to-zygotic transition.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1322
Series:
GSE11231
6 Samples
Download data: CEL
15.
Full record GDS3352

Juvenile hormone III effect on adult female insects

Analysis of whole bodies of yellow white (y, w) adult female insects topically treated with exogenous juvenile hormone (JH) III. JH can modulate immunity in insects. Results provide insight into the molecular mechanisms underlying JH regulation of innate immunity in insects.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL72
Series:
GSE9001
4 Samples
Download data: CEL, CHP, EXP, TIFF
16.
Full record GDS3255

Held out wing mutant embryos

Analysis of mutant embryos lacking both maternal and zygotic Held out wing (HOW), an RNA-binding protein (RBP) highly expressed in the mesoderm during early embryogenesis. how mutant embryos exhibit aberrant mesoderm spreading. Results provide insight into the role of HOW in mesoderm development.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL72
Series:
GSE7772
4 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3255
ID:
3255
17.
Full record GDS3227

Social isolation stress-induced aggression model

Analysis of heads of Canton-S males subjected to social isolation (single-housed). Social experience with conspecifics is an environmental influence on aggressiveness common to many species. Results provide insight into the molecular basis of the effect of social experience on aggressiveness.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 protocol sets
Platform:
GPL1322
Series:
GSE6994
6 Samples
Download data: CEL, CHP
18.
Full record GDS3072

Alcohol sensitivity model

Analysis of alcohol resistant and sensitive strains. Strains generated by artificial selection for alcohol sensitivity over multiple generations. Results provide insight into the molecular basis of alcohol sensitivity.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 gender, 2 other, 3 strain sets
Platform:
GPL1322
Series:
GSE7614
24 Samples
Download data: CEL, CHP
19.
Full record GDS2981

Embryos of various inbred lines: time course

Analysis of 5 and 8 hour embryos from 9 inbred lines. Results provide insight into the extent of gene expression variation in natural populations during early development.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, count, 2 age, 9 strain sets
Platform:
GPL1322
Series:
GSE8892
36 Samples
Download data: CEL, CHP
20.
Full record GDS2830

Strains resistant to environmental stresses

Analysis of several lines each selected for resistance to a different environmental stress factor. Results provide insight into the molecular and genetic mechanisms that promote adaptation to environmental stresses.
Organism:
Drosophila melanogaster
Type:
Expression profiling by array, transformed count, 8 strain sets
Platform:
GPL72
Series:
GSE6558
24 Samples
Download data: CEL
DataSet
Accession:
GDS2830
ID:
2830
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