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Items: 1 to 20 of 237

1.
Full record GDS5879

Pulmonary CDC11c+ cells from young and middle-age animals

Analysis of pulmonary CDC11c+ cells from 6-8 week and 10-13 month old C57BL/6 animals. CDC11c+ cells are key modulators of the immune response in the lung. Results provide insight into molecular mechanisms underlying the decline in immune function associated with aging.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL6885
Series:
GSE71868
8 Samples
Download data:
GEO
2.
Full record GDS5818

Normal liver developmental stages: embryonic and postnatal

Analysis of hepatoblasts, immature hepatocytes and hepatocytes from livers at different developmental timepoints (embryonic day 14, embryonic day 18, post-natal day 5, post-natal day 56). Results provide insight into molecular mechanisms underlying normal liver development.
Organism:
Mus musculus
Type:
Expression profiling by array, log2 ratio, 4 age, 3 cell type, 2 development stage sets
Platform:
GPL7202
Series:
GSE65063
11 Samples
Download data:
GEO (TXT)
3.
Full record GDS5660

Early postnatal skeletal muscle stem cells: time course

Analysis of myogenic stem cells called satellite cells (mSCs) FACS-sorted from the trunk of Pax3GFP/+ mice at postnatal days 1, 12, and 28, a period when most mSCs are in proliferation and quiescence states. Results provide insight into molecular basis of early postnatal skeletal muscle development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 2 tissue sets
Platform:
GPL1261
Series:
GSE65927
11 Samples
Download data:
GEO (CEL)
DataSet
Accession:
GDS5660
ID:
5660
4.
Full record GDS5642

Tendon development: embryonic limb tendon cells

Analysis of tendon cells isolated by FACS from forelimbs of embryonic day 11.5, E12.5 and E14.5 scleraxis (Scx)-GFP embryos. Basic helix-loop-helix transcription factor Scx is a specific tendon and ligament marker. Results provide insight into molecular pathways involved in tendon development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age sets
Platform:
GPL1261
Series:
GSE54207
9 Samples
Download data:
GEO (CEL, CHP)
DataSet
Accession:
GDS5642
ID:
5642
5.
Full record GDS5624

Epigenetic modifying reagents effect on a progressive hearing loss model: whole cochlea

Analysis of cochlea from 4 wk old DBA/2J males (a model of progressive hearing loss) injected for 8 wks with a combination of epigenetic modifiers l-methionine and valproic acid. Results provide insight into the effect of epigenetic modifications on the molecular mechanisms underlying hearing loss.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 age, 3 protocol sets
Platform:
GPL1261
Series:
GSE62173
16 Samples
Download data:
GEO (CEL)
6.
Full record GDS5528

White adipose tissue development

Analysis of developing white adipose tissues (WAT) of C57BL/6 animals at ages 15.5 embyronic days to 12 postnatal days. Results provide insight into the molecular mechanisms underlying the regulation of WAT development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 8 age sets
Platform:
GPL6885
Series:
GSE29502
8 Samples
Download data:
GEO
7.
Full record GDS5501

Progranulin deficiency effect on various brain regions: time course

Analysis of brain cortices, cerebella, and hippocampi of progranulin (GRN) deficient mutants at ages 2, 6, and 9 months. GRN mutations cause frontotemporal dementia. Results provide insight into the function of GRN in the central nervous system.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 2 gender, 3 genotype/variation, 3 tissue sets
Platform:
GPL6885
Series:
GSE31840
99 Samples
Download data:
GEO
8.
Full record GDS5438

Lung from cigarette smoke-related chronic obstructive pulmonary disease model: time course

Analysis of lung from cigarette smoke (CS)-treated C57BL/6N females at 4 and 6 months of age. Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD). Results provide insight into the molecular mechanisms underlying cigarette smoke-induced COPD.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age, 2 stress sets
Platform:
GPL6885
Series:
GSE52509
12 Samples
Download data:
GEO
DataSet
Accession:
GDS5438
ID:
5438
9.
Full record GDS5432

Age effect on corneal endothelium

Analysis of corneal endothelium from pediatric (4-11 years old) and adult (53-70 years old) donor corneas. Results provide insight into differential molecular expression between pediatric and adult corneal endothelial cells.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 age sets
Platform:
GPL11532
Series:
GSE58315
9 Samples
Download data:
GEO (CEL)
10.
Full record GDS5415

Model for Wilms tumor of the kidney: time course

Analysis of kidney tumors from Lin28a transgenics at 5 weeks and 4 months of age. Overexpression of heterochronic regulator Lin28 during kidney development promotes Wilms tumor formation. Results provide insight into the role of Lin28 in Wilms tumor formation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age, 2 disease state sets
Platform:
GPL6885
Series:
GSE56323
8 Samples
Download data:
GEO
11.
Full record GDS5412

Age effect on respiratory epithelium: distal trachea and carina region

Analysis of distal trachea and carina region of young (2 month) and old (14 month) C57Bl/6 females. Aging lungs are associated with a variety of structural and pathologic changes. Results provide insight into molecular mechanisms underlying age-related changes in respiratory epithelium.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL1261
Series:
GSE55162
8 Samples
Download data:
GEO (CEL)
12.
Full record GDS5286

Monocyte-derived dendritic cells from young and aged donors

Comparison of dendritic cells (DCs) from young (20 to 27 years) and aged (77 to 87 years) donors. DCs are antigen-presenting cells important in initiating and regulating innate and adaptive immune responses. Results provide insight into the molecular basis of the decline in DC function with age.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age sets
Platform:
GPL571
Series:
GSE58015
9 Samples
Download data:
GEO (CEL)
13.
Full record GDS5270

Infarct volume-variant inbred strains at two developmental stages: cerebral cortex

Analysis of cerebral cortex from C57BL/6J and C3H/J strains at post-natal day 1 and week 11. These strains share similar collateral vessel anatomy but exhibit significantly different infarct volume. Results provide insight into molecular mechanisms modulating infarct volume.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 age, 2 other, 2 strain sets
Platform:
GPL1261
Series:
GSE46443
12 Samples
Download data:
GEO (CEL)
14.
Full record GDS5233

Bisphenol A effect on the fetal urogenital sinus: time course

Analysis of urogenital sinuses (UGS) of male fetuses exposed to bisphenol A. BPA is a ubiquitous, estrogenic chemical used in the production of polycarbonate plastics. UGS examined at embryonic days 17 and 18, and postnatal day 0. Results provide insight into the molecular effects of BPA on UGS.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 3 agent sets
Platform:
GPL1261
Series:
GSE24928
9 Samples
Download data:
GEO (CEL, CHP)
DataSet
Accession:
GDS5233
ID:
5233
15.
Full record GDS5232

Early and late onset colorectal cancers

Analysis of primary colorectal cancer (CRC) tumors from patients diagnosed with CRC at an early age (28 to 53 years of age) and patients diagnosed at a later age (69 to 87 years). Results identify genes associated with early onset CRC.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 age, 2 gender, 2 tissue sets
Platform:
GPL2986
Series:
GSE25071
50 Samples
Download data:
GEO (TXT)
DataSet
Accession:
GDS5232
ID:
5232
16.
Full record GDS5226

Age effect on adipocytes of the bone marrow and epididymis

Analysis of bone marrow and epididymal adipocytes of 6 to 18 month old C57BL/6J animals. Aging is associated with impaired adipogenesis in various fat depots. An increase in bone marrow adiposity is associated with age-related bone disease.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 age, 2 cell type sets
Platform:
GPL6246
Series:
GSE25905
18 Samples
Download data:
GEO (CEL)
17.
Full record GDS5218

Resistance exercise effect on skeletal muscles of young and old adults

Analysis of vastus lateralis muscle biopsy samples from young (about 24 years old) and old (about 84 years old) adults before and after 12 weeks of progressive resistance training. Results provide insight into the molecular adaptation of the young and old skeletal muscle to resistance training.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age, 2 gender, 4 time sets
Platform:
GPL570
Series:
GSE28422
110 Samples
Download data:
GEO (CEL, CHP)
18.
Full record GDS5217

Resistance exercise effect on MHC I and MHC IIa muscle fibers of young and old women

Analysis of slow-twitch MHC I and fast-twitch MHC IIa muscle fibers from young and old women before and after 12 weeks of progressive resistance training. Fibers obtained from vastus lateralis. Results provide insight into the molecular adaptation of young and old MHC I and IIa fibers to exercise.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age, 14 individual, 4 time, 2 tissue sets
Platform:
GPL570
Series:
GSE28392
70 Samples
Download data:
GEO (CEL, CHP)
19.
Full record GDS5216

Age effect on the skeletal muscle

Analysis of vastus lateralis muscle biopsy samples from young (about 25 years old) and old (about 78 years old) adults. Subjects had not taken part in formal exercise. Results provide insight into the effect of age on basal gene expression in the skeletal muscle.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 age, 2 gender sets
Platform:
GPL570
Series:
GSE25941
36 Samples
Download data:
GEO (CEL, CHP)
20.
Full record GDS5204

Age effect on normal adult brain: frontal cortical region

Analysis of postmortem neuropathologically normal brain samples from the frontal cortical regions of young, middle aged, normal aged and extremely aged adults. Results provide insight into molecular mechanisms of aging in frontal cortical regions of the brain.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 age, 2 gender sets
Platform:
GPL570
Series:
GSE53890
41 Samples
Download data:
GEO (CEL)
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