GEO DataSet Links for PubMed (Select 36071064) - GEO DataSets

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Items: 2

Select item 2001792501.

A resource for integrated genomic analysis of the human liver

(Submitter supplied) In this study, we generated whole-transcriptome RNA-Seq from n=192 genotyped liver samples and used these data with existing data from the GTEx Project (RNA-Seq; PMID: 32913098) and previous liver eQTL (microarray; GSE32504, GSE25935, GSE9588, and GSE24293) studies to create an enhanced transcriptomic sequence resource in the human liver. Analyses of genotype-expression associations show pronounced enrichment of associations with genes of drug response. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
192 Samples

Download data: TXT

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Accession:: GSE179250

ID:: 200179250

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000261052.

Genetic identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue [Illumina SNP array]

(Submitter supplied) Most loci identified in genome wide association studies (GWAS) of complex traits reside in non-coding DNA and may contribute to phenotype via changes in gene regulation. The discovery of expression quantitative trait loci (‘eQTLs’) can thus be used to more precisely identify modest but real disease associations and provide insights into their underlying molecular mechanisms. This is particularly true for analyses of expression in non-transformed cells from tissues relevant to the complex traits of interest. more...