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Items: 2

1.

Transcriptional Alterations of Hamstring Muscle Contractures in Children with Cerebral Palsy

(Submitter supplied) Cerebral palsy is primarily an upper motor neuron disease that results in a spectrum of progressive movement disorders. Secondary to the neurological lesion, muscles from patients with cerebral palsy are often spastic and form debilitating contractures that limit range of motion and joint function. With no genetic component, the pathology of skeletal muscle in cerebral palsy is a response to aberrant neurological input in ways that are not fully understood. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4353
Platform:
GPL571
40 Samples
Download data: CEL, TXT
Series
Accession:
GSE31243
ID:
200031243
2.
Full record GDS4353

Cerebral Palsy: skeletal muscle biopsies

Analysis of gracilis and semitendinosus muscle biopsies from pediatric cerebral palsy (CP) patients. Muscles from CP patients are spastic and form contractures limiting range of motion and joint function. Results provide insight into molecular basis of skeletal muscle response to CP.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 2 tissue sets
Platform:
GPL571
Series:
GSE31243
40 Samples
Download data: CEL

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