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Items: 3

1.

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
83 Samples
Download data: CEL
Series
Accession:
GSE38912
ID:
200038912
2.

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers [ChIP-Seq]

(Submitter supplied) Heat-Shock Factor 1 (HSF1), master regulator of the heat-shock response, facilitates malignant transformation, cancer cell survival and proliferation in model systems. The common assumption is that these effects are mediated through regulation of heat-shock protein (HSP) expression. However, the transcriptional network that HSF1 coordinates directly in malignancy and its relationship to the heat-shock response have never been defined. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL9052 GPL15433 GPL11154
63 Samples
Download data: XLS
Series
Accession:
GSE38901
ID:
200038901
3.

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers [gene expression]

(Submitter supplied) Heat-Shock Factor 1 (HSF1), master regulator of the heat-shock response, facilitates malignant transformation, cancer cell survival and proliferation in model systems. The common assumption is that these effects are mediated through regulation of heat-shock protein (HSP) expression. However, the transcriptional network that HSF1 coordinates directly in malignancy and its relationship to the heat-shock response have never been defined. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL3921
20 Samples
Download data: CEL
Series
Accession:
GSE38232
ID:
200038232
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