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Amplified genes are not necessarily over expressed, they can be unchanged or down regulated in cervical cancer cell lines [SNP array data]

(Submitter supplied) Several copy number altered regions (CNA) have been identified in the genome of cervical cancer, especially amplifications of 3q and 5p. However, the contribution of those alterations to cervical carcinogenesis is still a matter of debate, since genome-wide, there is a lack of correlation between CNAs and gene expression. In this study, we investigated whether the CNAs in cell lines (CaLo, CasKi, HeLa, SiHa), at a gene-by-gene level, are related to changes in gene expression. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL2005 GPL2004
84 Samples
Download data: CEL, CHP
Series
Accession:
GSE29244
ID:
200029244

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