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Items: 2

1.

Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response.

(Submitter supplied) Maternal immune activation is a risk factor for the development of schizophrenia and autism. Infections during pregnancy activate the mother's immune system and alter the fetal environment with sub-sequence effects of CNS function and behavior in the offspring, but the cellular and molecular links between infection-induced altered fetal development and risk for neuropsychiatric disorders are unknown. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS4429
Platform:
GPL6247
19 Samples
Download data: CEL
Series
Accession:
GSE34058
ID:
200034058
2.
Full record GDS4429

Fetal brain response to maternal immune activation induced by lipopolysaccharide

Analysis of fetal brains following maternal immune activation (MIA) induced by treating pregnant dams with lipopolysaccharide. MIA is a risk factor for the development of schizophrenia and autism. Results provide insight into the effect of MIA on the fetal brain at the molecular level.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL6247
Series:
GSE34058
19 Samples
Download data: CEL

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