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Items: 2

1.

Frequent driver mutations in histone H3.3 and chromatin remodeling genes in paediatric glioblastoma

(Submitter supplied) Whole exome sequencing identified frequent driver mutations in a series of paediatric glioblastomas We used microarray-based profiling to investigate differences in gene expression according to mutational status of driver genes
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4477
Platform:
GPL570
27 Samples
Download data: CEL
Series
Accession:
GSE34824
ID:
200034824
2.
Full record GDS4477

Pediatric glioblastoma brain tumors: histone H3.3 mutations

Analysis of pediatric glioblastoma (GBM) tumors with mutations in H3F3A gene. Mutation of key residues in histone H3.3 are specific to GBM and highly prevalent in children and young adults. Results indicate that defects in chromatin architecture underlie pediatric GBM pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 genotype/variation sets
Platform:
GPL570
Series:
GSE34824
27 Samples
Download data: CEL
DataSet
Accession:
GDS4477
ID:
4477

Supplemental Content

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