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Expression profiles of the NuB4/HAT-B complex and histone knockouts

(Submitter supplied) Dynamic modification of histone proteins plays a key role in regulating gene expression. However, histones themselves can also be dynamic, which potentially affects the stability of histone modifications. To determine the molecular mechanisms of histone turnover we developed a parallel screening method for epigenetic regulators by analyzing chromatin states on DNA barcodes. Histone turnover was quantified by employing a genetic pulse-chase technique called RITE, which was combined with chromatin immunoprecipitation and high-throughput sequencing. more...
Organism:
Saccharomyces cerevisiae
Type:
Expression profiling by array
Platform:
GPL11232
36 Samples
Download data: PDF, TXT
Series
Accession:
GSE30168
ID:
200030168

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