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Glioblastoma microvesicles transport RNA and proteins

(Submitter supplied) Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells. By incorporating an mRNA for a reporter protein into these microvesicles, we demonstrate that messages delivered by microvesicles are translated by recipient cells. These microvesicles are also enriched in angiogenic proteins and stimulate tubule formation by endothelial cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL4133
2 Samples
Download data: TXT
Series
Accession:
GSE13470
ID:
200013470

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