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Cell type-specific induction of mRNA in human B cells and monocytes by IFN-beta

(Submitter supplied) Compared to primary human monocytes in whole blood cultures, few B cells activated STAT1 in response to stimulation of 2000 IU/ml IFN-beta for 45 minutes. Because activation of STAT1 leads to apoptosis induction, we tested the hypothesis that less pro-apoptotic genes are induced in B cells as compared to monocytes. Manuscript titled: Major differences in the responses of primary human leukocyte subsets to IFN-beta. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6104
6 Samples
Download data:
GEO (TXT)
Series
Accession:
GSE23307
ID:
200023307

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