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Phenotypic and Molecular Characterization of the Claudin-low Intrinsic Subtype of Breast Cancer

(Submitter supplied) In breast cancer, gene expression analyses have defined five tumor subtypes, each of which has unique biologic and prognostic features. Here, we characterize the recently identified claudin-low tumor subtype as showing low to absent expression of luminal differentiation markers, high enrichment for epithelial-to-mesenchymal transition markers, immune response genes, and cancer stem cell–like features. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
7 related Platforms
372 Samples
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Series
Accession:
GSE18229
ID:
200018229

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