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Items: 3

1.

The human reticulocyte transcriptome (HG-U133_Plus2.0)

(Submitter supplied) RNA from circulating blood reticulocytes was utilized to provide a robust description of genes transcribed at the final stages of erythroblast maturation. After depletion of leukocytes and platelets, Affymetrix HG-U133Plus 2.0 arrays were hybridized with probe from total RNA isolated from blood sampled from 6 umbilical cords and 6 healthy adult humans.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3814
Platform:
GPL570
12 Samples
Download data: CEL
Series
Accession:
GSE17639
ID:
200017639
2.

Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

(Submitter supplied) MicroRNA are ~22nt-long small non-coding RNA that negatively regulate protein expression through mRNA degradation or translational repression in eukaryotic cells. Based upon their importance in regulating development and terminal differentiation in model systems, erythrocyte microRNA profiles were examined at birth and in adults to determine if changes in their abundance coincide with the developmental phenomenon of hemoglobin switching. more...
Organism:
Human gammaherpesvirus 4; Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL8949
8 Samples
Download data: GPR
Series
Accession:
GSE17405
ID:
200017405
3.
Full record GDS3814

Fetal and adult reticulocytes

Comparison of reticulocytes from adult peripheral blood and umbilical cord blood. Hemoglobin (Hb) composition switches around the time of birth from fetal Hb to adult Hb. Together with microRNA profiling, results provide insight into the role of microRNAs in fetal-to-adult Hb switching.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 development stage sets
Platform:
GPL570
Series:
GSE17639
12 Samples
Download data: CEL
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