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Genome-Wide Screen of Promoter Methylation Identifies Novel Markers for Tumor Development in Melanoma

(Submitter supplied) Background: DNA methylation is an important component of epigenetic modifications that influences the transcriptional machinery and is aberrant in many human diseases. In particular, dysregulation of promoter methylation in cancer has already been shown to be associated with repression of tumor suppressors and activation of oncogenes. In addition, detection of altered promoter methylation status is suitable for the design of diagnostic or prognostic tests. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL6484 GPL6602
43 Samples
Download data: PAIR
Series
Accession:
GSE13706
ID:
200013706

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