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Early Response and Outcome in High-Risk Childhood Acute Lymphoblastic Leukemia: A Children’s Oncology Group Study

(Submitter supplied) The cure rate for childhood ALL has improved considerably in part because therapy is routinely tailored to the predicted risk of relapse. Various clinical and laboratory variables are used in current risk-stratification schemes, but many children who fail therapy lack adverse prognostic factors at initial diagnosis. Using gene expression analysis, we have identified genes and pathways in a NCI high-risk childhood B-precursor ALL cohort at diagnosis that may play a role in early blast regression as correlated with the Day 7 marrow status. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
99 Samples
Download data: CEL, CHP, EXP
Series
Accession:
GSE7440
ID:
200007440

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