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Effect of the HF diet and Akt1-mediated muscle growth on gene expression in liver tissue.

(Submitter supplied) In contrast to the well-established role of oxidative muscle fibers in regulating fatty acid oxidation and whole body metabolism, little is known that about the function of fast/glycolytic muscle fibers in these processes. Here, we generated a skeletal muscle-specific, conditional transgenic mouse expressing a constitutively-active form of Akt1. Transgene activation led to muscle hypertrophy due to the growth of type IIb muscle fibers, which was accompanied by an increase in strength. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL8321
11 Samples
Download data: CEL
Series
Accession:
GSE9484
ID:
200009484

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