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Gene expression programs of histologically distinct stages of prostate carcinogenesis in Nkx3.1; Pten mutant mice

(Submitter supplied) Key histological and growth progression characteristics of human prostate cancer are phenocopied in mouse models that have been subjected to androgen level depletion and engineered for hemizygosity of candidate prostate cancer tumor suppressor genes Nkx3.1 and Pten. To characterize their relative transcriptomes and identify a genomic basis for their relevance to human prostate cancers, we compared mouse prostate tumors expression profiles to those from a panel of human prostate cancer isolates and to normal and benign prostates. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL339
26 Samples
Download data: CEL
Series
Accession:
GSE15943
ID:
200015943

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