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Items: 2

1.

Creatine increases health and life span in mice

(Submitter supplied) Here we show that oral creatine (Cr) supplementation leads to increased life span in mice. Treated mice showed improved neurobehavioral performance, decreased accumulation of the aging pigment lipofuscin and upregulation of “anti-aging” genes in brain. As Cr is virtually free of adverse effects, it may be a promising food supplement for healthy aging in man. Keywords: creatine, life span, neurobehavioural performance, microarray, oxidative stress, aging
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS2765
Platform:
GPL1261
13 Samples
Download data: CEL, XML
Series
Accession:
GSE5140
ID:
200005140
2.
Full record GDS2765

Creatine effect on the brain

Analysis of brains of C57Bl/6J animals fed a creatine supplemented diet for 6 months. Creatine has a neuroprotective effect in animal models of neurodegenerative diseases. Results provide insight into the molecular basis of this neuroprotective effect.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL1261
Series:
GSE5140
13 Samples
Download data: CEL, XML
DataSet
Accession:
GDS2765
ID:
2765

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