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Full record GDS3641

Methyltransferase Hypb deficiency effect on the yolk sac during development

Analysis of yolk sacs from E9 and E10.5 embryos lacking Hypb, a histone H3 lysine 36-specific methytransferase. Hypb deficiency results in lethality at E10.5-E11.5 and severe vascular defects in the embryo, yolk sac, and placenta. Results provide insight into the function of Hypb in development.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 development stage, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE10113
12 Samples
Download data: CEL

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