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Links from GEO DataSets

Items: 4

1.
Full record GDS4422

Interleukin-25-induced pulmonary inflammation model: Type 2 myeloid cells and other inflammatory subsets

Analysis of inflammatory cell types from lungs of 4get females that received daily intra-tracheal injections of IL-25 for 4 days to induce antigen-independent type 2 inflammation. Results provide insight into role of IL-25 and its receptor in innate and adaptive pulmonary type 2 immune responses.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 4 cell type sets
Platform:
GPL1261
Series:
GSE36392
9 Samples
Download data: CEL
2.

Expression data from pulmonary Type 2 Myeloid (T2M) cells, Eosinophils, Neutrophils, and Macrophages, from IL-25 treated 4get mice

(Submitter supplied) Many symptoms associated with allergic asthma result from the sequelae of type 2 inflammation. Interleukin (IL)-25 promotes type 2 inflammatory responses, and T2M cells represent an IL-4 and IL-13 producing granulocytic IL-25 responsive population. We used microarrays to characterize the gene expression profile of T2M cells, and compared T2M cells to other inflammatory subsets (eosinophils, neutrophils, and macrophages) in the lungs of mice with IL-25-induced pulmonary inflammation.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4422
Platform:
GPL1261
9 Samples
Download data: CEL
Series
Accession:
GSE36392
ID:
200036392
3.

Lung Natural Helper cells

(Submitter supplied) Natural Helper cells constitute a unique lineage of Th2-cytokine producting innate lymphocytes, here we characterize the gene expression profile of non-stimulated or PMA/ionomycin-stimulated Natural Helper cells from naive C57Bl/6 mouse lungs. We used microarrays to detail the gene expression profile of stimulated and unstimulated lung Natural Helper cells in mice.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6246
5 Samples
Download data: CEL
Series
Accession:
GSE36057
ID:
200036057
4.

Expression data in CD4 T cells from lungs of PBS or house dust mite treated mice

(Submitter supplied) CD4 T cells are essential mediators of the asthmatic process. We used the clinically relevant allergen house dust mites to induce signs of allergy in mice and performed gene expression arrays specifically on CD4 T cells infiltrating the lung Reference: IL-21-producing CD4+ T cells promote type 2 immunity to house dust mites
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL16570
6 Samples
Download data: CEL
Series
Accession:
GSE72005
ID:
200072005
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