GEO DataSets

Analysis of macrophage-like THP-1 cells treated with Stx1 or lipopolysaccharides (LPS). Shiga toxins (Stxs) are bacterial cytotoxins produced by enteric pathogens Shigella dysenteriae and some serotypes of E. coli. Results provide further insight into the effects of Stxs on cell function.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 agent sets

Platform:

GPL570

Series:

GSE19315

9 Samples

Download data: CEL

(Submitter supplied) Shiga toxins (Stxs) are bacterial cytotoxins produced by the enteric pathogens Shigella dysenteriae serotype 1 and some serotypes of Escherichia coli that cause bacillary dysentery and hemorrhagic colitis, respectively. To date, approaches to studying the capacity of Stxs to alter gene expression in intoxicated cells have been limited to individual genes. However, it is known that many of the signaling pathways activated by Stxs regulate the expression of multiple genes in mammalian cells. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4041

Platform:

GPL570

9 Samples

Download data: CEL

(Submitter supplied) Effect of human macrophages phagocytosis on the global transcriptome of EDL933 at different time. Infection of THP-1 with EDL933. Application of SCOTS technique to have cDNA. Hybridation on microarray. Reference: EDL933 in RPMI medium Keywords: stres response, host-bacteria response, time-course

Organism:

Escherichia coli

Type:

Expression profiling by array

Platform:

GPL6178

16 Samples

Download data

(Submitter supplied) We compared the gene expression patterns of macrophages infected with S. oralis wild type and SpxB KO, a strain that does not produce H2O2.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL21810

8 Samples

Download data: TXT