GEO DataSets

Analysis of primary ovarian tumors from patients with high depressive symptoms. Results provide insight into the contribution of biobehavioral factors such as such as stress, depression, and social support to the molecular progression of cancer.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 individual sets

Platform:

GPL96

Series:

GSE9116

10 Samples

Download data: CEL

(Submitter supplied) Gene expression profiling was carried out on splenocyte mRNA samples collected from 10 animals subject to repeated social threat (pooled into 2 groups of 5) and 10 animals subject to non-threatening control conditions (pooled into 2 groups of 5). The primary research question is whether gene expression differs in CD11b+ splenocytes from animals exposed to social threat vs non-threatening control conditions. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

4 Samples

Download data: CEL

(Submitter supplied) Gene expression profiling was carried out on prefrontal cortex mRNA samples collected from 10 animals subject to repeated social threat (pooled into 2 groups of 5) and 10 animals subject to non-threatening control conditions (pooled into 2 groups of 5). The primary research question is whether gene expression differs in prefrontal cortex tissue from animals exposed to social threat vs non-threatening control conditions. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

4 Samples

Download data: CEL

(Submitter supplied) Gene expression profiling was carried out on primary ovarian carcinomas from 10 patients. The primary research question is whether gene expression differs in tissues from individuals with high vs low symptoms of psychological depression. Keywords: Risk prediction

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3525

Platform:

GPL96

10 Samples

Download data: CEL

(Submitter supplied) TNF time course series of HelA tet off cells cultured in presence or absence of Dox TNF is a pro-inflammatory cytokine that controls expression of inflammatory genetic networks. Although the Nuclear Factor-kB (NF-kB) pathway is crucial for mediating cellular TNF responses, the complete spectrum of NF-kB dependent genes is unknown. In this study, we used a tetracycline-regulated cell line expressing an NF-kB inhibitor to systematically identify NF-kB dependent genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1212

Platform:

GPL8300

32 Samples

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Temporal analysis of the effect of tumor necrosis factor (TNF) on gene expression in HeLa cells with NF-kappaB inactivated. NF-kappaB inactivated with 2 ug/ml doxycycline. Cells examined at various time points following stimulation with 25 ng/ml TNF. Results identify potential targets of NF-kappaB.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 4 time sets

Platform:

GPL8300

Series:

GSE2624

32 Samples

Download data

(Submitter supplied) Peripheral blood leukocytes of three human donors (Donors 2, 4, and 5) were isolated from blood bank buffy-coat preparations by Ficoll-Hypaque density gradient centrifugation, and T-cells were purified with high affinity negative selection human CD3+ T-cell enrichment columns. The cells were resuspended in RPMI-1640 with 10% FCS with approximately 3-8 millions cells/mL at room temperature overnight. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2035

Platform:

GPL201

12 Samples

Download data: CEL, EXP, RPT

Analysis of T cells costimulated with concanavalin A and anti-CD28 antibody in a vectorless gravity environment, which approximates true freefall or microgravity experienced in spaceflight. Results provide insight into the molecular basis of the altered immune function experienced by astronauts.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 individual, 2 protocol, 2 stress sets

Platform:

GPL201

Series:

GSE1709

12 Samples

Download data: CEL, EXP, RPT

(Submitter supplied) Background and Purpose Aneurysmal subarachnoid hemorrhage, almost always from saccular intracranial aneurysm (sIA), is a devastating form of stroke that affects working age population. Cellular and molecular mechanisms predisposing to the rupture of the sIA wall are largely unknown. Such knowledge would facilitate the design of novel diagnostic tools and therapies for the sIA disease. Methods We compared the whole genome expression profile of eleven ruptured sIA wall samples, resected at a median of 15 hours after rupture, to that of eight unruptured ones. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

19 Samples

Download data: CEL

(Submitter supplied) Gene expression profiles of human HNSCC lines were compared with human normal keratinocytes by 24K cDNA microarray. The ten HNSCC analyzed are derived by the University of Michigan (UM-SCC), representing late stage SCC of different anatomic sites. Principle component analysis and hierarchical gene clustering classified ten cancer cell lines into two subsets, and associated each of the subsets with a distinctive p53 status. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6569

14 Samples

Download data: GPR

(Submitter supplied) We used complementary DNA (cDNA) microarrays to compare gene expression patterns in ovarian cancers associated with BRCA1 or BRCA2 mutations with gene expression patterns in sporadic epithelial ovarian cancers and to identify patterns common to both hereditary and sporadic tumors.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL21962

61 Samples

Download data: GPR

(Submitter supplied) Gene expression profiling was carried out on peripheral blood leukocytes from 14 healthy older adults. The primary research question is whether gene expression differs in individuals experiencing chronically high levels of social isolation (by UCLA Loneliness Scale) vs chronically low levels of social isolation. Keywords: Risk prediction

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3207

Platform:

GPL96

14 Samples

Download data: CEL

Analysis of leukocytes from individuals experiencing chronically high levels of subjective social isolation (loneliness). Social environment is known to influence human health. Results provide insight into transcriptional alterations in the immune system induced by chronic social isolation.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 individual sets

Platform:

GPL96

Series:

GSE7148

14 Samples

Download data: CEL