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Links from GEO DataSets

Items: 10

1.
Full record GDS3482

X-linked inhibitor of apoptosis XIAP depletion effect on a colorectal cancer cell line

Analysis of early and late passage HCT116 colon cancer cells depleted for X-linked inhibitor of apoptosis (XIAP). XIAP is overexpressed in the majority of NCI 60 cell lines compared to normal cells suggesting a potential role as a therapeutic target in a wide spectrum of malignancies.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 other, 3 protocol sets
Platform:
GPL570
Series:
GSE11618
18 Samples
Download data: CEL
DataSet
Accession:
GDS3482
ID:
3482
2.

Stable XIAP knockdown in HCT116 colon cancer cells

(Submitter supplied) X-linked inhibitor of apoptosis (XIAP) is the most potent endogenous caspase inhibitor preventing cell death via caspase-9, -7 and -3 (initiator and executioner caspase pathways). Using short hairpin RNA (shRNA) against XIAP, stably expressed in a parent HCT116 human colon cancer cell line, a series of clones have been developed. XIAP mRNA levels were established by RT-PCR, the four X (XIAP knockdown) clonal cell lines show 82-93% reduction in XIAP mRNA when compared to the four L (luciferase control) cell lines. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3482
Platform:
GPL570
18 Samples
Download data: CEL
Series
Accession:
GSE11618
ID:
200011618
3.

Gene expression variation induced by loss of the CD146 mRNA in MDA-MB-231

(Submitter supplied) Metastasis is a complex process involving loss of adhesion, migration, invasion and proliferation of cancer cells. Cell adhesion molecules play a pivotal role in this phenomenon by regulating cell-cell and cell-matrix interactions. CD146 (MCAM) is associated with advanced tumor stage in melanoma, prostate and ovarian cancers. For this study, the MDA-MB-231 cell line was used as a prototypic mesenchymal and invasive cell line, spontaneously expressing high levels of CD146. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
5 Samples
Download data: CEL
Series
Accession:
GSE11951
ID:
200011951
4.

Expression profiles of mouse glioma-initiating cell-like subclones

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
8 Samples
Download data: CEL
Series
Accession:
GSE17101
ID:
200017101
5.

Expression profiling of sox11-expressing glioma-initiating cell-like cells

(Submitter supplied) To identify factors involved in tumorigenicity of glioma-initiating cells (GICs), we compared gene expression in GIC-like cells with and without sox11 expression.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
4 Samples
Download data: CEL
Series
Accession:
GSE17076
ID:
200017076
6.

Expression profiling of mouse glioma-initiating cell-like cells (GICs) and non-GICs

(Submitter supplied) To identify factors involved in glioma-initiating cells (GICs), we compared gene expression between GIC-like cells and non-GICs.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
4 Samples
Download data: CEL
Series
Accession:
GSE17062
ID:
200017062
7.

Gene expression profiling of human breast cancers and cancer cell lines

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
98 Samples
Download data: CEL
Series
Accession:
GSE12790
ID:
200012790
8.

Gene expression profiling of 51 human breast cancer cell lines

(Submitter supplied) Basal gene expression levels were determined by global gene expression profiling of breast cancer cell lines. Molecular subtype was determined using gene expression and HER2 status assesses by HER2 FISH analysis. Keywords: Basal gene expression (no stimulation or timecourse)
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
51 Samples
Download data: CEL
Series
Accession:
GSE12777
ID:
200012777
9.

Gene expression changes upon expression of activated versions of MEK1 and HRAS in MCF10A cells

(Submitter supplied) MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors Cells were lysed 24 hours post-transfection with collection of total RNA and protein Keywords: Oncogene inducation of gene expression changes
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
17 Samples
Download data: CEL
Series
Accession:
GSE12764
ID:
200012764
10.

Gene expression profiling of 30 human breast cancers

(Submitter supplied) We used microarrays to profile 30 human primary breast tumors and determine global gene expression patterns and molecular subtypes Keywords: Basal gene expression in human tumor samples
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
30 Samples
Download data: CEL
Series
Accession:
GSE12763
ID:
200012763
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