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Links from GEO DataSets

Items: 7

1.

Avian resistance to Campylobacter jejuni colonization is associated with an intestinal immunogene expression signature identified by mRNA sequencing.

(Submitter supplied) RNAseq analysis of caecal tissue from 14 C. jejuni-susceptible and 14 C. jejuni-resistant birds from a single population of infected chickens was conducted in order to identify gene expression associated with resistance to colonization. Significantly higher expression of genes involved in the innate immune response, cytokine signaling, B cell and T cell activation and immunoglobulin production, as well as the renin-angiotensin system was observed in resistant birds.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9385
28 Samples
Download data: TSV, TXT
Series
Accession:
GSE44341
ID:
200044341
2.

Global gene expression profile of chicken cecal tonsil in response to campylobacter jejuni challenge in broiler lines

(Submitter supplied) It is essential to understand host response to Campylobacter jejuni infection in order to genetically improve resistance to its colonization in chickens. A custom Agilent chicken 44K array was used to examine gene expression profiles after Campylobacter jejuni infection of two broiler lines (A and B). Day-old chicks were orally inoculated with C. jejuni. After day 7 post-infection, the cecal tonsil was collected for total RNA isolation and cecal content for bacteria burden quantification. more...
Organism:
Gallus gallus
Type:
Expression profiling by array
Platform:
GPL6413
24 Samples
Download data: GPR
Series
Accession:
GSE10257
ID:
200010257
3.

CGH Analysis of C. jejuni isolates

(Submitter supplied) We performed microarray CGH analysis of 104 neuropathogenic and enteritis only stains of C. jejuni. Keywords: Individual hybridizations, CGH
Organism:
Campylobacter jejuni
Type:
Genome variation profiling by array
Platforms:
GPL2681 GPL352
104 Samples
Download data
Series
Accession:
GSE3579
ID:
200003579
4.

Campylobacter jejuni Cj1000 regulon

(Submitter supplied) Transcriptional regulation mediates adaptation of pathogens to environmental stimuli and is important for host colonisation. The Campylobacter jejuni genome sequence reveals a surprisingly small set of regulators, mostly of unknown function, suggesting an intricate regulatory network. Interestingly, C. jejuni lacks the homologues of ubiquitous regulators involved in stress response found in many other Gram-negative bacteria. more...
Organism:
Campylobacter jejuni
Type:
Expression profiling by array
Platform:
GPL6293
21 Samples
Download data: CSV
Series
Accession:
GSE43792
ID:
200043792
5.

Analysis of the Activity and Regulon of the Two-component Regulatory System Composed by Cjj1484 and Cjj1483 of Campylobacter jejuni

(Submitter supplied) Campylobacter jejuni is a leading cause of bacterial diarrheal disease and a frequent commensal of the intestinal tract of poultry and other animals. For optimal growth and colonization of hosts, C. jejuni employs two-component regulatory systems (TCSs) to monitor environmental conditions and promote proper expression of specific genes. We analyzed the potential of C. jejuni Cjj81176_1484 (Cjj1484) and Cjj81176_1483 (Cjj1483) to encode proteins of a cognate TCS that influences expression of genes possibly important for C. more...
Organism:
Campylobacter jejuni
Type:
Expression profiling by array
Platform:
GPL19897
18 Samples
Download data: TXT
Series
Accession:
GSE66942
ID:
200066942
6.

Intestinal development in two divergent chicken lines (X and Y)

(Submitter supplied) The objective of this study was to investigate the impact of genotypic variation on both early microbial colonization of the gut and functional development of intestinal tissue. From two genetically diverse chicken lines intestinal content samples were taken for microbiota analyzes and intestinal tissue samples were extracted for gene expression analyzes, both at three subsequent time-points (days 0, 4, and 16).
Organism:
Gallus gallus
Type:
Expression profiling by array
Platform:
GPL18890
45 Samples
Download data: TXT
Series
Accession:
GSE65042
ID:
200065042
7.

Global transcriptional analysis of Campylobacter jejuni NCTC 11168 in response to epinephrine and norepinephrine.

(Submitter supplied) During colonization in the host gastrointestinal tract, the enteric bacteria Campylobacter jejuni is exposed to a variety of signaling molecules including the catecholamine hormones epinephrine (Epi) and norepinephrine (NE). NE has been determined to stimulate the growth of C. jejuni as well as increase its pathogenicity. To investigate the mechanisms of NE or Epi on the biology of C. jejuni, the global gene expression profiles of C. more...
Organism:
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Type:
Expression profiling by array
Platform:
GPL19679
10 Samples
Download data: TXT
Series
Accession:
GSE65187
ID:
200065187
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