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Links from GEO DataSets

Items: 4

1.

Acute venous hypertension induces local release of inflammatory cytokines and endothelial activation in humans

(Submitter supplied) Background: Venous hypertension is often present in advanced and in acute decompensated heart failure (HF). However, it is unclear whether high intravenous pressure can cause alterations in homeostasis by promoting inflammation and endothelial cell (EC) activation. We used an experimental model of acute, local venous hypertension to study the changes in circulating inflammatory mediators and EC phenotype that occur in response to biomechanical stress. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4773
Platform:
GPL570
24 Samples
Download data: CEL
Series
Accession:
GSE38783
ID:
200038783
2.
Full record GDS4773

Peripheral venous congestion model: endothelial cells

Analysis of venous endothelial cells (EC) following experimental venous hypertension treatment, a venous stress test designed to model peripheral venous congestion. Results provide insight into the molecular consequences of peripheral acute venous congestion in ECs.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 12 individual, 2 protocol sets
Platform:
GPL570
Series:
GSE38783
24 Samples
Download data: CEL
3.

Transcriptomic profile of human preadipocyte treated by macrophages from adipose tissue

(Submitter supplied) Obesity is characterized by a chronic auto-inflammation of the hypertrophied white adipose tissue (WAT) associated with metabolic and vascular complications. WAT of obese subjects produces inflammatory factors like cytokines (IL6, TNF-alpha) and chemokines (CCL2 and IL-8) originating mainly from the accumulated macrophages. WAT macrophages profoundly affect adipose cell biology leading in particular to the inflammation of the adipocytes and altered differentiation of their precursors, the pre-adipocytes. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13379
5 Samples
Download data: GPR
Series
Accession:
GSE28445
ID:
200028445
4.

Right ventricular failure due to pulmonary banding

(Submitter supplied) Right ventricular failure was induced thourgh pulmonary banding in 11 pigs. Right ventricular failure was defined as a SRVP >50 mmHg during two hours. After right ventricular failure was induced, half the pigs were treated with a Glenn-shunt combined with pulmonary banding for one hour, and the other half served as control group with pulmonary banding only. The aim was to study the change in global gene expression during right ventricular failure due to pulmonary banding, and the effect of volume unloading during pulmonary banding.
Organism:
Sus scrofa
Type:
Expression profiling by array
Platform:
GPL3533
33 Samples
Download data: CEL
Series
Accession:
GSE47814
ID:
200047814
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